Evidence map›Paper›PMID 31337705›Full record

ArticleThe Journal of biological chemistry2019

Sulfated Lewis A trisaccharide on oviduct membrane glycoproteins binds bovine sperm and lengthens sperm lifespan.

Sudipta Dutta, Kazuhiro Aoki, Kankanit Doungkamchan, Michael Tiemeyer, Nicolai Bovin, David J Miller

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 33 citations in OpenAlex.

  1. From reservoir to rendezvous: the journey of sperm through the oviduct.Reproduction, fertility, and development · 2026
    Review
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  16. Effects of a NanoencapsulatedAntioxidants (Basel, Switzerland) · 2021
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Sudipta DuttaDepartment of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801.
Kazuhiro AokiComplex Carbohydrate Research Center, University of Georgia, Athens, Georgia 30602.
Kankanit DoungkamchanDepartment of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801.
Michael TiemeyerComplex Carbohydrate Research Center, University of Georgia, Athens, Georgia 30602.
Nicolai BovinShemyakin Institute of Bioorganic Chemistry, Moscow 117997, Russia.
David J MillerDepartment of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801. Electronic address: djmille@illinois.edu.
University of Illinois Urbana-Champaign · USUniversity of Georgia · USInstitute of Bioorganic Chemistry · RU

Funding

TR&D1: Stem Cell and Induced Pluripotent Stem Cell Resources (Pages 116-134)P41GM103490 · NIGMS · UNIVERSITY OF GEORGIA · PI PIERCE, J. MICHAEL · 2012 to 2018
$13.7M
Accumulation, Storage, and Release of Sperm in the OviductR01HD095841 · NICHD · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI DAVID Joel MILLER · 2018 to 2026
$2.5M
Development of high-throughput workflow for glycosphingolipid analysis and annotationR21AI129873 · NIAID · UNIVERSITY OF GEORGIA · PI AOKI, KAZUHIRO, RANZINGER, RENE · 2016 to 2017
$582k
NIAID NIH HHS R21 AI129873NICHD NIH HHS R01 HD095841NIGMS NIH HHS P41 GM103490
6 · The paper itself

Abstract

A fraction of sperm deposited at mating or insemination reaches the oviduct isthmus, where sperm are retained and thereby form a reservoir. This reservoir delays capacitation, prevents polyspermy, selects a fertile population of sperm, and, foremost, increases sperm lifespan. The molecular interactions underlying the formation of a sperm reservoir are becoming clearer in mammals. Sperm lectins bind to oviductal glycans to form the reservoir. Herein, we found that the highest percentage of bovine sperm bound to the 3'-

Indexed as

AnimalsCattleEpithelial CellsLewis Blood Group AntigensLife ExpectancyMaleMembrane GlycoproteinsOligosaccharidesSpermatozoaSulfatesLewis a oligosaccharideLewis Blood Group AntigensMembrane GlycoproteinsOligosaccharidesSulfatescell adhesioncell deathfertilizationglycobiologyglycomicslectinLewis structureoviductreceptorssperm

Identifiers

PMID31337705
PMCPMC6737213
OpenAlexW2964136162

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.