Evidence map›Paper›PMID 31337664›Full record

ArticleDisease models & mechanisms2019

Zebrafish modeling of intestinal injury, bacterial exposures and medications defines epithelial

Ling-Shiang Chuang, Joshua Morrison, Nai-Yun Hsu, Philippe Ronel Labrias, Shikha Nayar, Ernie Chen, Nicole Villaverde, Jody Ann Facey, Gilles Boschetti, Mamta Giri and 5 more

Open access · goldAbstract read
In one paragraph

Article in Disease models & mechanisms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 54 citations in OpenAlex.

  1. Review
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  13. Wear and tear of the intestinal visceral musculature by intrinsic and extrinsic factors.Developmental dynamics : an official publication of the American Association of Anatomists · 2022
    Article
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  17. The complex role of prostaglandin EAmerican journal of physiology. Regulatory, integrative and comparative physiology · 2021
    Review
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  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Ling-Shiang ChuangDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0001-5054-1305
Joshua MorrisonDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Nai-Yun HsuDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0003-3321-6388
Philippe Ronel LabriasDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0001-7281-9339
Shikha NayarDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0001-8519-4569
Ernie ChenDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0003-1573-7577
Nicole VillaverdeDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0002-1421-8305
Jody Ann FaceyDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Gilles BoschettiDepartment of Oncological Science, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0003-4039-7607
Mamta GiriDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0002-9019-515X
Mireia Castillo-MartinDepartments of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Tin Htwe ThinDepartments of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0002-7891-1459
Yashoda SharmaDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Jaime ChuDepartment of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0002-9291-8630
Judy H ChoDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA judy.cho@mssm.edu.ORCID 0000-0002-7959-0466
Icahn School of Medicine at Mount Sinai · US

Funding

Inflammatory Bowel Disease Genetics Consortium Data Coordinating CenterU01DK062429 · NIDDK · YALE UNIVERSITY · PI CHO, JUDY H. · 2002 to 2016
$16.8M
Precision IBD via genetics and genomics: integrating International and multi-omic datasets, expanding studies in diverse populations, and defining mechanisms of unmet clinical needs in IBDU24DK062429 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Ling-shiang Chuang, Ron Do · 2017 to 2026
$13.9M
Yale University Inflammatory Bowel Disease Genetics Research CenterU01DK062422 · NIDDK · YALE UNIVERSITY · PI Ling-shiang Chuang · 2002 to 2026
$10.8M
Integrative Genomic Analyses of Macrophages in Crohns DiseaseR01DK106593 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CHO, JUDY H. · 2016 to 2020
$3.8M
A novel role for p53 in congenital disorders of glycosylationK08DK101340 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CHU, JAIME C · 2013 to 2016
$554k
NIDDK NIH HHS K08 DK101340NIDDK NIH HHS R01 DK106593NIDDK NIH HHS U01 DK062422NIDDK NIH HHS U01 DK062429NIDDK NIH HHS U24 DK062429
6 · The paper itself

Abstract

Genome-wide association studies have identified over 200 genomic loci associated with inflammatory bowel disease (IBD). High-effect risk alleles define key roles for genes involved in bacterial response and innate defense. More high-throughput

Indexed as

AcidsAnimalsAutophagyBacterial ProteinsDextran SulfateDinoprostoneDisease Models, AnimalEnterocytesEpitheliumHumansInflammatory Bowel DiseasesIntestinesLysosomesModels, BiologicalMucinsMucusAcidsBacterial ProteinsDextran SulfateDinoprostoneMucinsCrohn's diseaseDSS injury modelEpithelial barrierIBDLysosome-rich enterocytes

Identifiers

PMID31337664
PMCPMC6737949
OpenAlexW2962715733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.