ArticleBMC plant biology2019
Flower bud proteome reveals modulation of sex-biased proteins potentially associated with sex expression and modification in dioecious Coccinia grandis.
Article in BMC plant biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 17 citations in OpenAlex.
- Developmental and Molecular Insights into AgNOPlants (Basel, Switzerland) · 2026Article
- Temperature-dependent sex expression in cucurbits and beyond: mechanisms, reproductive plasticity, and breeding implications.Frontiers in plant science · 2026Review
- Comparative Proteomic Analysis of Floral Buds before and after Opening in Walnut (International journal of molecular sciences · 2024Article
- Comparative proteomic analysis of papaya bud flowers reveals metabolic signatures and pathways driving hermaphrodite development.Scientific reports · 2024Article
- Multi-Omics Analysis Reveals Intricate Gene Networks Involved in Female Development in Melon.International journal of molecular sciences · 2023Article
- Comparative transcriptome analysis of dioecious floral development in Trachycarpus fortunei using Illumina and PacBio SMRT sequencing.BMC plant biology · 2023Article
- Combined Transcriptome and Proteome Analysis Provides Insights into Petaloidy in Pomegranate.Plants (Basel, Switzerland) · 2023Article
- SWATH-MS based quantitive proteomics reveal regulatory metabolism and networks of androdioecy breeding system in Osmanthus fragrans.BMC plant biology · 2021Article
- Genome-Wide Association Studies for Sex Determination and Cross-Compatibility in Water Yam (Plants (Basel, Switzerland) · 2021Article
- Comparative RNA-Seq analysis reveals genes associated with masculinization in female Cannabis sativa.Planta · 2021Article
- Development of a Virus-Induced Gene Silencing System for Dioecious Coccinia grandis.Molecular biotechnology · 2020Article
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundDioecy is an important sexual system wherein, male and female flowers are borne on separate unisexual plants. Knowledge of sex-related differences can enhance our understanding in molecular and developmental processes leading to unisexual flower development. Coccinia grandis is a dioecious species belonging to Cucurbitaceae, a family well-known for diverse sexual forms. Male and female plants have 22A + XY and 22A + XX chromosomes, respectively. Previously, we have reported a gynomonoecious form (22A + XX) of C. grandis bearing morphologically hermaphrodite flowers (GyM-H) and female flowers (GyM-F). Also, we have showed that foliar spray of AgNO
resultsTo identify sex-related differences, total proteomes from male, female, GyM-H and Ag-H flower buds at early and middle stages of development were analysed by label-free proteomics. Protein search against the cucumber protein sequences (Phytozome) as well as in silico translated C. grandis flower bud transcriptome database, resulted in the identification of 2426 and 3385 proteins (FDR ≤ 1%), respectively. The latter database was chosen for further analysis as it led to the detection of higher number of proteins. Identified proteins were annotated using BLAST2GO pipeline. SWATH-MS-based comparative abundance analysis between Female_Early_vs_Male_Early, Ag_Early_vs_Female_Early, GyM-H_Middle_vs_Male_Middle and Ag_Middle_vs_ Male_Middle led to the identification of 650, 1108, 905 and 805 differentially expressed proteins, respectively, at fold change ≥1.5 and P ≤ 0.05. Ethylene biosynthesis-related candidates as highlighted in protein interaction network were upregulated in female buds compared to male buds. AgNO
conclusionOverall, current proteomic analysis provides insights in the identification of key proteins governing dioecy and unisexual flower development in cucurbitaceae, the second largest horticultural family in terms of economic importance. Also, our results suggest that the ethylene-mediated stamen inhibition might be conserved in dioecious C. grandis similar to its monoecious cucurbit relatives. Further, male-biased proteins associated with pollen germination and tube growth identified here can help in understanding pollen fertility.
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