Evidence map›Paper›PMID 31337271›Full record

ReviewAnnual review of pharmacology and toxicology2020

Pharmacology of Small- and Intermediate-Conductance Calcium-Activated Potassium Channels.

Brandon M Brown, Heesung Shim, Palle Christophersen, Heike Wulff

Open access · greenAbstract readReview
In one paragraph

Review in Annual review of pharmacology and toxicology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 111 citations in OpenAlex.

  1. Structural basis for the subtype-selective activation of KStructure (London, England : 1993) · 2026
    Article
  2. Article
  3. Guidelines for evaluating endothelial function in vascular tissue.American journal of physiology. Heart and circulatory physiology · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Development of a novel acaricide, acynonapyr.Journal of pesticide science · 2025
    Article
  11. Design and structural basis of selective 1,4-dihydropyridine inhibitors of the calcium-activated potassium channel KProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Evolution of two-pore domain potassium channels and their gene expression in zebrafish embryos.Developmental dynamics : an official publication of the American Association of Anatomists · 2024
    Article
  18. Repurposing the KTranslational stroke research · 2024
    Article
  19. Article
  20. Review

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Brandon M BrownDepartment of Pharmacology, University of California, Davis, California 95616, USA; email: hwulff@ucdavis.edu.
Heesung ShimDepartment of Pharmacology, University of California, Davis, California 95616, USA; email: hwulff@ucdavis.edu.
Palle ChristophersenSaniona A/S, DK-2750 Ballerup, Denmark; email: pc@sanonia.com.
Heike WulffDepartment of Pharmacology, University of California, Davis, California 95616, USA; email: hwulff@ucdavis.edu.
University of California, Davis · USSaniona (Denmark) · DK

Funding

UC Davis Clinical and Translational Science CenterUL1TR001860 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KENYON, NICHOLAS J., LYLES, COURTNEY REES · 2016 to 2025
$47.3M
Training and Education CoreU54NS079202 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEIN, PAMELA J · 2012 to 2021
$35.7M
UC Davis CTSC TL1 Administrative Supplement to Recognize Excellence in Diversity, Equity, Inclusion, and Accessibility MentorshipTL1TR001861 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MEDICI, VALENTINA · 2016 to 2025
$4.7M
Structure Assisted Design of SK Channel Selective ActivatorsR21NS101876 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI WULFF, HEIKE · 2017 to 2018
$410k
NCATS NIH HHS TL1 TR001861NCATS NIH HHS UL1 TR001860NINDS NIH HHS R21 NS101876NINDS NIH HHS U54 NS079202
6 · The paper itself

Abstract

The three small-conductance calcium-activated potassium (K

Indexed as

AnimalsBinding SitesCardiovascular DiseasesHumansIntermediate-Conductance Calcium-Activated Potassium ChannelsNervous System DiseasesPotassium Channel BlockersSmall-Conductance Calcium-Activated Potassium ChannelsIntermediate-Conductance Calcium-Activated Potassium ChannelsPotassium Channel BlockersSmall-Conductance Calcium-Activated Potassium Channelscalcium-activated potassium channelgating modulationKCa2.2KCa2.3KCa3.1

Identifiers

PMID31337271
PMCPMC9615427
OpenAlexW2962791178

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.