Evidence map›Paper›PMID 31337251›Full record

ArticleJournal of the American Heart Association2019

Arrhythmias and Adaptations of the Cardiac Conduction System in Former National Football League Players.

Philip Aagaard, Shishir Sharma, David A McNamara, Parag Joshi, Colby R Ayers, James A de Lemos, Andrew E Lincoln, Bryan Baranowski, Kyle Mandsager, Elizabeth Hill and 7 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 1 country.

Philip AagaardDepartment of Cardiovascular Medicine, Heart and Vascular Institute Cleveland Clinic Foundation Cleveland OH.
Shishir SharmaDivision of Cardiology UT Southwestern Medical Center Dallas TX.
David A McNamaraDivision of Cardiology UT Southwestern Medical Center Dallas TX.
Parag JoshiDivision of Cardiology UT Southwestern Medical Center Dallas TX.
Colby R AyersDivision of Cardiology UT Southwestern Medical Center Dallas TX.
James A de LemosDivision of Cardiology UT Southwestern Medical Center Dallas TX.
Andrew E LincolnMedStar Sports Medicine Baltimore MD.
Bryan BaranowskiDepartment of Cardiovascular Medicine, Heart and Vascular Institute Cleveland Clinic Foundation Cleveland OH.
Kyle MandsagerDepartment of Cardiovascular Medicine, Heart and Vascular Institute Cleveland Clinic Foundation Cleveland OH.
Elizabeth HillCedars-Sinai Heart Institute Los Angeles CA.
Lon CastleDepartment of Cardiovascular Medicine, Heart and Vascular Institute Cleveland Clinic Foundation Cleveland OH.
James GentryDepartment of Cardiovascular Medicine, Heart and Vascular Institute Cleveland Clinic Foundation Cleveland OH.
Richard LangDepartment of Cardiovascular Medicine, Heart and Vascular Institute Cleveland Clinic Foundation Cleveland OH.
Reginald E DunnMedStar Sports Medicine Baltimore MD.
Kezia AlexanderMedStar Sports Medicine Baltimore MD.
Andrew M TuckerMedStar Sports Medicine Baltimore MD.
Dermot PhelanDepartment of Cardiovascular Medicine, Heart and Vascular Institute Cleveland Clinic Foundation Cleveland OH.
Cleveland Clinic · USMedStar Health · USSouthwestern Medical CenterSouthwestern Medical Center · USThe University of Texas Southwestern Medical Center · US

Funding

UT Southwestern Center for Translational Medicine (UL1/KL2/TL1)UL1TR001105 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2013 to 2017
$24.5M
NCATS NIH HHS UL1 TR001105
6 · The paper itself

Abstract

Background Habitual high-intensity endurance exercise is associated with increased atrial fibrillation (AF) risk and impaired cardiac conduction. It is unknown whether these observations extend to prior strength-type sports exposure. The primary aim of this study was to compare AF prevalence in former National Football League (NFL) athletes to population-based controls. The secondary aim was to characterize other conduction system parameters. Methods and Results This cross-sectional study compared former NFL athletes (n=460, age 56±12 years, black 47%) with population-based controls of similar age and racial composition from the cardiovascular cohort Dallas Heart Study-2 (n=925, age 54±9 years, black 53%). AF was present in 28 individuals (n=23 [5%] in the NFL group; n=5 [0.5%] in the control group). After controlling for other cardiovascular risk factors in multivariable regression analysis, former NFL participation remained associated with a 5.7 (95% CI: 2.1-15.9, P<0.001) higher odds ratio of AF. Older age, higher body mass index, and nonblack race were also independently associated with higher odds ratio of AF, while hypertension and diabetes mellitus were not. AF was previously undiagnosed in 15/23 of the former NFL players. Previously undiagnosed NFL players were rate controlled and asymptomatic, but 80% had a CHA

Indexed as

Adaptation, PhysiologicalAdultAgedAtrial FibrillationBlack or African AmericanCross-Sectional StudiesFootballHeart Conduction SystemHumansMaleMiddle AgedPrevalenceUnited StatesWhite Peopleathlete's heartatrial fibrillationconduction diseaseNational Football League

Identifiers

PMID31337251
PMCPMC6761649
OpenAlexW2964058039

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.