Evidence map›Paper›PMID 31337196›Full record

ArticleClinical endoscopy2019

Effectiveness of Endoscopic Sclerotherapy with Aluminum Potassium Sulfate and Tannic Acid as a Non-Surgical Treatment for Internal Hemorrhoids.

Yuichi Tomiki, Jun Aoki, Shunsuke Motegi, Rina Takahashi, Toshiaki Hagiwara, Yu Okazawa, Kosuke Mizukoshi, Masaya Kawai, Shinya Munakata, Shun Ishiyama and 2 more

Open access · goldAbstract read
In one paragraph

Article in Clinical endoscopy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Latest Research Trends on the Management of Hemorrhoids.Journal of the anus, rectum and colon · 2025
    Review
  3. Review
  4. Sclerotherapy in Hemorrhoids.The Indian journal of surgery · 2023
    Review
  5. Article
  6. Progress in Endoscopic Treatment of Hemorrhoids.Journal of translational internal medicine · 2020
    Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Yuichi TomikiDepartment of Coloproctological Surgery, Juntendo University, Faculty of Medicine, Tokyo, Japan.
Jun AokiDepartment of Coloproctological Surgery, Juntendo University, Faculty of Medicine, Tokyo, Japan.
Shunsuke MotegiDepartment of Coloproctological Surgery, Juntendo University, Faculty of Medicine, Tokyo, Japan.
Rina TakahashiDepartment of Coloproctological Surgery, Juntendo University, Faculty of Medicine, Tokyo, Japan.
Toshiaki HagiwaraDepartment of Coloproctological Surgery, Juntendo University, Faculty of Medicine, Tokyo, Japan.
Yu OkazawaDepartment of Coloproctological Surgery, Juntendo University, Faculty of Medicine, Tokyo, Japan.
Kosuke MizukoshiDepartment of Coloproctological Surgery, Juntendo University, Faculty of Medicine, Tokyo, Japan.
Masaya KawaiDepartment of Coloproctological Surgery, Juntendo University, Faculty of Medicine, Tokyo, Japan.
Shinya MunakataDepartment of Coloproctological Surgery, Juntendo University, Faculty of Medicine, Tokyo, Japan.
Shun IshiyamaDepartment of Coloproctological Surgery, Juntendo University, Faculty of Medicine, Tokyo, Japan.
Kiichi SugimotoDepartment of Coloproctological Surgery, Juntendo University, Faculty of Medicine, Tokyo, Japan.
Kazuhiro SakamotoDepartment of Coloproctological Surgery, Juntendo University, Faculty of Medicine, Tokyo, Japan.
Juntendo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsSclerotherapy with aluminum potassium sulfate and tannic acid (ALTA) has a potent effect on internal hemorrhoids. In this retrospective study, we compared the effects of endoscopic ALTA therapy and standard ALTA therapy.

methodsWe investigated patients who underwent treatment for internal hemorrhoids at our institution between 2014 and 2016. They were divided into a standard ALTA group (n=33, treated using proctoscopy) and an endoscopic ALTA group (n=48). We compared the clinical findings between the 2 groups.

resultsThere were no intergroup differences in background factors. The mean ALTA dose was 21.9±7.2 mL and 17.8±3.4 mL in the standard and endoscopic ALTA groups, respectively (p<0.01). Adverse events occurred in 4 patients (12.1%) from the standard ALTA group and 6 patients (12.5%) from the endoscopic ALTA group. In both groups, the patients reported good satisfaction with the therapeutic effect at 1 month after the procedure. Hemorrhoids recurred in 2 patients (6.3%) from the standard ALTA group and 4 patients (8.3%) from the endoscopic ALTA group.

conclusionEndoscopic ALTA sclerotherapy is equivalent to standard ALTA therapy in terms of efficacy, adverse events, and recurrence. Therefore, it is a useful non-surgical option for patients with internal hemorrhoids who prefer a less invasive treatment.

Indexed as

EndoscopyHemorrhoidsSurgeryTherapy

Identifiers

PMID31337196
PMCPMC6900292
OpenAlexW2963824281

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.