Evidence map›Paper›PMID 31336842›Full record

ArticleJournal of clinical medicine2019

Intestinal Fatty Acid Binding Protein, a Biomarker of Intestinal Barrier, is Associated with Severity of Psoriasis.

Mariusz Sikora, Albert Stec, Magdalena Chrabaszcz, Anna Waskiel-Burnat, Michal Zaremba, Malgorzata Olszewska, Lidia Rudnicka

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 82 citations in OpenAlex.

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  7. Gut-skin axis: Emerging insights for gastroenterologists-a narrative review.World journal of gastrointestinal pathophysiology · 2025
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  17. Periodontal bacteria influence systemic diseases through the gut microbiota.Frontiers in cellular and infection microbiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mariusz SikoraDepartment of Dermatology, Medical University of Warsaw, Koszykowa 82a, 02-008 Warsaw, Poland. msikora@wum.edu.pl.ORCID 0000-0002-6162-9916
Albert StecDepartment of Dermatology, Medical University of Warsaw, Koszykowa 82a, 02-008 Warsaw, Poland.
Magdalena ChrabaszczDepartment of Dermatology, Medical University of Warsaw, Koszykowa 82a, 02-008 Warsaw, Poland.
Anna Waskiel-BurnatDepartment of Dermatology, Medical University of Warsaw, Koszykowa 82a, 02-008 Warsaw, Poland.
Michal ZarembaDepartment of Dermatology, Medical University of Warsaw, Koszykowa 82a, 02-008 Warsaw, Poland.
Malgorzata OlszewskaDepartment of Dermatology, Medical University of Warsaw, Koszykowa 82a, 02-008 Warsaw, Poland.
Lidia RudnickaDepartment of Dermatology, Medical University of Warsaw, Koszykowa 82a, 02-008 Warsaw, Poland.
Medical University of Warsaw · PL

Funding

Ministerstwo Nauki i Szkolnictwa Wyższego 1M4/PM1/17/17
6 · The paper itself

Abstract

Alterations of intestinal microbiota play a significant role in the pathogenesis of psoriasis. Dysbiosis may cause disruption of the intestinal barrier, which contributes to immune activation by translocation of microbial antigens and metabolites. Intestinal fatty acid binding protein (I-FABP) serves as a biomarker of enterocyte damage. The aim of this study was to investigate clinical and metabolic factors affecting plasma concentration of I-FABP in patients with psoriasis. Eighty patients with psoriasis and 40 control subjects were enrolled in the study. Serum I-FABP (243.00 (108.88-787.10) vs. 114.38 (51.60-241.60) pg/ml,

Indexed as

gut barrierintestinal fatty acid binding proteinmicrobiomepsoriasis

Identifiers

PMID31336842
PMCPMC6678629
OpenAlexW2959607197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.