ReviewViruses2019
Human Norovirus Cultivation in Nontransformed Stem Cell-Derived Human Intestinal Enteroid Cultures: Success and Challenges.
Open access · goldAbstract readReview
In one paragraph
Review in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 1 pooled it
9.7field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
75 citing papers in PubMed, 1 synthesis or guideline pooled it, 132 citations in OpenAlex.
- Rotavirus vaccines in Africa and Norovirus genetic diversity in children aged 0 to 5 years old: a systematic review and meta-analysis : Rotavirus vaccines in Africa and Norovirus genetic diversity.BMC infectious diseases · 2024Pooled it
- Plscr1 inhibits murine norovirus entry.bioRxiv : the preprint server for biology · 2026Article
- Serum IgA proteomics reveals clonal composition and neutralization of dimeric and monomeric IgA repertoires against human norovirus.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Temperature and developmental stage govern intestinal susceptibility to human coronavirus 229E.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Silk Scaffold Crypt-Villus Geometry Combined With L-WRN Feeder Cells Sustains Spatially Organized Epithelial Proliferation and Multilineage Differentiation.Journal of biomedical materials research. Part A · 2026Article
- Proof of concept: targeted protein degradation of the stress granules component G3BP1 as an antiviral strategy against norovirus infection.Antimicrobial agents and chemotherapy · 2026Article
- Variable and conserved B cell epitopes of GII.4 human noroviruses.Journal of virology · 2026Review
- Organoids Gone Viral: A Comprehensive Review on Human Organoid Models to Study Viral Pathogenesis.Viruses · 2026Review
- Mechanisms of Norovirus Immunity: Implications for Vaccine Design.Annual review of pathology · 2026Review
- Inhibition of interferon signaling improves rabbit calicivirus replication in biliary organoid cultures.Journal of virology · 2025Article
- Trim7 does not have a role in the restriction of murine norovirus infectionJournal of virology · 2025Article
- BTP2 restricts Tulane virus and human norovirus replication independent of store-operated calcium entry.Journal of virology · 2025Article
- Norovirus replication, host interactions and vaccine advances.Nature reviews. Microbiology · 2025Review
- B cell lines fail to support efficient rhesus enteric calicivirus and human norovirus replication.Journal of virology · 2025Article
- Proteomics as a complementary approach to measure norovirus infection in clinical samples.Virology · 2025Review
- Exploring non-alcohol-based disinfectant: virucidal efficacy of arginine and Zinc chloride against feline calicivirus.Frontiers in microbiology · 2025Article
- Structural and stability differences among GI norovirus virus-like particles produced in silkworm-baculovirus expression vector system.Frontiers in microbiology · 2025Article
- Human respiratory organoids sustained reproducible propagation of human rhinovirus C and elucidation of virus-host interaction.Nature communications · 2024Article
- Ultraviolet (UV-C) Light Systems for the Inactivation of Feline Calicivirus and Tulane Virus in Model Fluid Foods.Food and environmental virology · 2024Article
- Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 1 institution in 2 countries.
Mary K EstesDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA. mestes@bcm.edu.
Khalil EttayebiDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.
Victoria R TengeDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0002-9429-7161
Kosuke MurakamiDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.
Umesh KarandikarDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.
Shih-Ching LinDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0003-2960-5348
B Vijayalakshmi AyyarDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0001-6775-9546
Nicolas W Cortes-PenfieldDepartment of Medicine, Infectious Diseases, Baylor College of Medicine, Houston, TX 77030, USA.
Kei HagaDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.
Frederick H NeillDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.
Antone R OpekunDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0003-4837-6480
James R BroughmanDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0003-3456-6187
Xi-Lei ZengDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.
Sarah E BluttDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.
Sue E CrawfordDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.
Sasirekha RamaniDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0001-5631-8534
David Y GrahamDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.
Robert L AtmarDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.
Baylor College of Medicine · US
Funding
Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI DAVID R ROWLEY · 2007 to 2026
$73.9MX-ray Crystallographic Studies on CalicivirusesP01AI057788 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI ATMAR, ROBERT L., ESTES, MARY KOLB · 2004 to 2024
$34.4MTissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Geoffrey A Preidis · 2001 to 2026
$28.3MResearch Training in Infections and ImmunityT32AI055413 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI GIORDANO, THOMAS P, MYSOREKAR, INDIRA U · 2003 to 2024
$3.2MNCI NIH HHS P30 CA125123NIAID NIH HHS P01 AI057788NIAID NIH HHS T32 AI055413NIDDK NIH HHS P30 DK056338
Abstract
Noroviruses, in the genus
Indexed as
Caliciviridae InfectionsEpithelial CellsHost-Pathogen InteractionsHumansIntestinal MucosaNorovirusStem CellsVirus CultivationVirus Replicationhuman norovirus cultivationintestinal enteroids/organoidsvirus neutralization and inactivation
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.