Evidence map›Paper›PMID 31336690›Full record

ArticleCancers2019

Flavopereirine Suppresses the Growth of Colorectal Cancer Cells through P53 Signaling Dependence.

Jhy-Ming Li, Yun-Ching Huang, Yi-Hung Kuo, Chih-Chung Cheng, Feng-Che Kuan, Shun-Fu Chang, Ying-Ray Lee, Chih-Chien Chin, Chung-Sheng Shi

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jhy-Ming LiDivision of Colon and Rectal Surgery, Department of Surgery, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan.
Yun-Ching HuangDivision of Urology, Department of Surgery, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan.ORCID 0000-0002-5683-8406
Yi-Hung KuoDivision of Colon and Rectal Surgery, Department of Surgery, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan.
Chih-Chung ChengGraduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.
Feng-Che KuanGraduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.
Shun-Fu ChangDepartment of Medical Research and Development, Chang Gung Memorial Hospital Chiayi Branch, Chiayi 61363, Taiwan.
Ying-Ray LeeDepartment of Medical Research, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chiayi 60002, Taiwan.ORCID 0000-0002-0349-0960
Chih-Chien ChinDivision of Colon and Rectal Surgery, Department of Surgery, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan. ccchin@cgmh.org.tw.
Chung-Sheng ShiDivision of Colon and Rectal Surgery, Department of Surgery, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan. csshi@mail.cgu.edu.tw.ORCID 0000-0002-5548-7675
Chang Gung University · TWChiayi Chang Gung Memorial Hospital · TWChia-Yi Christian Hospital · TW

Funding

Chang Gung Memorial Hospital CMRPG6F0581-3Chang Gung Memorial Hospital CMRPG6G0291Ministry of Science and Technology MOST103-2314-B-182A-105Ministry of Science and Technology MOST105-2314-B-182A-096
6 · The paper itself

Abstract

Colorectal cancer (CRC) is a significant cause of morbidity and mortality worldwide. The outcome of CRC patients remains poor. Thus, a new strategy for CRC treatment is urgently needed. Flavopereirine is a β-carboline alkaloid extracted from

Indexed as

colorectal cancerFlavopereirineP53

Identifiers

PMID31336690
PMCPMC6678721
OpenAlexW2963901158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.