ArticleBiomolecules2019
A Simple and Efficient Molecularly Imprinted Electrochemical Sensor for the Selective Determination of Tryptophan.
Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 60 citations in OpenAlex.
- Advanced Electrochemical Sensors for Rapid and Sensitive Monitoring of Tryptophan and Tryptamine in Clinical Diagnostics.Biosensors · 2025Review
- Ultra-sensitive electrochemical sensor based on molecularly imprinted polydopamine grafted with MWCNT-COOH for tryptophan detection.Mikrochimica acta · 2025Article
- Fabrication of MIP-based sensors for femtomolar detection of kynurenic acid for early diagnosis of neurodegenerative diseases.ACS omega · 2025Article
- Zirconium Molybdate Nanocomposites' Sensing Platform for the Sensitive and Selective Electrochemical Detection of Adefovir.Molecules (Basel, Switzerland) · 2022Article
- Review
- Application of Janus Particles in Point-of-Care Testing.Biosensors · 2022Review
- Advances in Metal-Organic Frameworks MIL-101(Cr).International journal of molecular sciences · 2022Review
- Preparation and evaluation of the anti-cancer properties of RGD-modified curcumin-loaded chitosan/perfluorohexane nanocapsulesHeliyon · 2022Article
- Molecularly Imprinted Polymer-Amyloid Fibril-Based Electrochemical Biosensor for Ultrasensitive Detection of Tryptophan.Biosensors · 2022Article
- Electrochemically Deposited Molecularly Imprinted Polymer-Based Sensors.Sensors (Basel, Switzerland) · 2022Review
- A Review of Sensors and Biosensors Modified with Conducting Polymers and Molecularly Imprinted Polymers Used in Electrochemical Detection of Amino Acids: Phenylalanine, Tyrosine, and Tryptophan.International journal of molecular sciences · 2022Review
- Research progress on detection techniques for point-of-care testing of foodborne pathogens.Frontiers in bioengineering and biotechnology · 2022Review
- Laser-Induced Graphene Electrodes Modified with a Molecularly Imprinted Polymer for Detection of Tetracycline in Milk and Meat.Sensors (Basel, Switzerland) · 2021Article
- Review
- Sensitive Voltammetric Sensor for Tryptophan Detection by Using Polyvinylpyrrolidone Functionalized Graphene/GCE.Nanomaterials (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this paper, a tryptophan (Trp) molecularly imprinted chitosan film was prepared on the surface of an acetylene black paste electrode using chitosan as the functional polymer, Trp as the template molecule and sulfuric acid as the crosslinking agent. The surface morphologies of non-imprinted and imprinted electrodes were characterized by scanning electron microscopy (SEM). The formation of hydrogen bonds between the functional polymer and the template molecule was confirmed by infrared spectroscopy. Some factors affecting the performance of the imprinted electrode such as the concentration of chitosan, the mass ratio of chitosan to Trp, the dropping amount of the chitosan-Trp mixture, the solution pH, and the accumulation potential and time were discussed. The experimental results show that the imprinted electrode exhibit good affinity and selectivity for Trp. The dynamic linear ranges of 0.01-4 M, 4-20 M and 20-100 M were obtained by second derivative linear sweep voltammetry, and the detection limit was calculated to be 8.0 nM. The use of the imprinted electrode provides an effective method for eliminating the interference of potentially interfering substances. In addition, the sensor has high sensitivity, reproducibility and stability, and can be used for the determination of Trp in pharmaceutical preparations and human serum samples.
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