Evidence map›Paper›PMID 31336605›Full record

ArticleInternational journal of molecular sciences2019

Bakuchiol Suppresses Inflammatory Responses Via the Downregulation of the p38 MAPK/ERK Signaling Pathway.

Hye-Sun Lim, Yu Jin Kim, Bu-Yeo Kim, Soo-Jin Jeong

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
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  6. microPublication biology · 2025
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  9. A review ofFrontiers in pharmacology · 2024
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  15. Article
  16. Review
  17. Immune-Enhancing Effects ofJournal of microbiology and biotechnology · 2021
    Article
  18. Article
  19. Ethanolic Fruit Extract ofEvidence-based complementary and alternative medicine : eCAM · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Hye-Sun LimHerbal Medicine Resources Research Center, Korea Institute of Oriental Medicine, Naju-si, Jeollanam-do 58245, Korea. qplhs1015@gmail.com.ORCID 0000-0003-0727-3864
Yu Jin KimClinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea.ORCID 0000-0001-5152-9439
Bu-Yeo KimClinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea.
Soo-Jin JeongClinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea. qp1015@kiom.re.kr.
Korea Institute of Oriental Medicine · KRChungnam National University · KR

Funding

Korea Institute of Oriental Medicine K17293Korea Institute of Oriental Medicine KSN1515293
6 · The paper itself

Abstract

The purpose of the present study was to evaluate the effects of bakuchiol on the inflammatory response and to identify the molecular mechanism of the inflammatory effects in a lipopolysaccharide (LPS)-stimulated BV-2 mouse microglial cell line and mice model. The production of prostaglandin E

Indexed as

AnimalsAnti-Inflammatory AgentsCell SurvivalCytokinesExtracellular Signal-Regulated MAP KinasesInflammation MediatorsLipopolysaccharidesMAP Kinase Signaling SystemMiceMicrogliap38 Mitogen-Activated Protein KinasesPhenolsAnti-Inflammatory AgentsbakuchiolCytokinesExtracellular Signal-Regulated MAP KinasesInflammation MediatorsLipopolysaccharidesp38 Mitogen-Activated Protein KinasesPhenolsbakuchiolinflammatory responseMAPK phosphorylationmicroglianeuroinflammation

Identifiers

PMID31336605
PMCPMC6678636
OpenAlexW2963116610

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.