Evidence map›Paper›PMID 31336593›Full record

ArticleJournal of clinical medicine2019

Phenotypic Characterization of Diffuse Large B-Cell Lymphoma Cells and Prognostic Impact.

Julie Devin, Alboukadel Kassambara, Angélique Bruyer, Jérôme Moreaux, Caroline Bret

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Julie DevinCNRS UMR9002, Institute of Human Genetics, 34090 Montpellier, France.
Alboukadel KassambaraCNRS UMR9002, Institute of Human Genetics, 34090 Montpellier, France.
Angélique BruyerCNRS UMR9002, Institute of Human Genetics, 34090 Montpellier, France.
Jérôme MoreauxCNRS UMR9002, Institute of Human Genetics, 34090 Montpellier, France.
Caroline BretCNRS UMR9002, Institute of Human Genetics, 34090 Montpellier, France. c-bret@chu-montpellier.fr.
Hôpital Saint Eloi · FRInstitut de Génétique Humaine · FRUniversité de Montpellier · FR

Funding

Institut National Du Cancer INCa_Inserm_DGOS_12553Institut National Du Cancer PLBIO18; 2018-160
6 · The paper itself

Abstract

Multiparameter flow cytometry (MFC) is a fast and cost-effective technique to evaluate the expression of many lymphoid markers in mature B-cell neoplasms, including diffuse large B cell lymphoma (DLBCL), which is the most frequent non-Hodgkin lymphoma. In this study, we first characterized by MFC the expression of 27 lymphoid markers in 16 DLBCL-derived cell lines to establish a robust algorithm for their authentication. Then, using the expression profile in DLBCL samples of the genes encoding B lymphoid markers that are routinely investigated by MFC, we built a gene expression-based risk score, based on the expression level of

Indexed as

biomarkerDLBCLdrug resistanceflow cytometryprognosis

Identifiers

PMID31336593
PMCPMC6678649
OpenAlexW2964137626

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.