Evidence map›Paper›PMID 31336004›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2019

Zeolitic Imidazolate Framework-8 as pH-Sensitive Nanocarrier for "Arsenic Trioxide" Drug Delivery.

Romy Ettlinger, Natalia Moreno, Dirk Volkmer, Kornelius Kerl, Hana Bunzen

Open access · hybridAbstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Romy EttlingerChair of Solid State and Materials Chemistry, Institute of Physics, University of Augsburg, Universitaetsstraße 1, 86159, Augsburg, Germany.
Natalia MorenoPediatric Hematology and Oncology, University Children's Hospital Muenster, Albert-Schweitzer-Campus 1, 48149, Muenster, Germany.ORCID http://orcid.org/0000-0002-3386-8098
Dirk VolkmerChair of Solid State and Materials Chemistry, Institute of Physics, University of Augsburg, Universitaetsstraße 1, 86159, Augsburg, Germany.ORCID http://orcid.org/0000-0002-8105-2157
Kornelius KerlPediatric Hematology and Oncology, University Children's Hospital Muenster, Albert-Schweitzer-Campus 1, 48149, Muenster, Germany.ORCID http://orcid.org/0000-0002-5676-8102
Hana BunzenChair of Solid State and Materials Chemistry, Institute of Physics, University of Augsburg, Universitaetsstraße 1, 86159, Augsburg, Germany.ORCID http://orcid.org/0000-0003-1824-0291
University of Augsburg · DEUniversity Hospital Münster · DE

Funding

Else Kröner-Fresenius-Stiftung 2016_A181
6 · The paper itself

Abstract

Previous results revealed that arsenic trioxide might be used as promising therapeutic agent for the treatment of some solid tumours as atypical teratoid rhabdoid tumours (ATRT). However, in order to become an approved drug for solid tumour treatment, the active formulation has to get more efficient and feasible-but at the same time less toxic. One of the possibilities to achieve this dichotomy is to use nanomedicine tools. Herein, we report on the Zn-based metal-organic framework ZIF-8 (Zeolitic Imidazolate Framework-8) which turned out to be a promising candidate for the delivery of As

Indexed as

Arsenic TrioxideDrug Delivery SystemsHydrogen-Ion ConcentrationNanoparticlesNeoplasmsPolyethylene GlycolsZeolitesArsenic TrioxidePolyethylene GlycolsZeolitesarseniccancerdrug deliverymetal-organic frameworksnanoparticle

Identifiers

PMID31336004
PMCPMC6856809
OpenAlexW2964178016

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.