Evidence map›Paper›PMID 31335837›Full record

ReviewJournal of pediatric gastroenterology and nutrition2019

Biliary Atresia as a Disease Starting In Utero: Implications for Treatment, Diagnosis, and Pathogenesis.

Krupa R Mysore, Benjamin L Shneider, Sanjiv Harpavat

Abstract readReview
In one paragraph

Review in Journal of pediatric gastroenterology and nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
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  6. Review
  7. Article
  8. Rectal budesonide: A potential game changer after Kasai hepatoportoenterostomy.Journal of pediatric gastroenterology and nutrition · 2025
    Article
  9. Incidence and outcome of biliary atresia in the United Arab Emirates: A multicenter national study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2025
    Article
  10. Article
  11. The Assessment and Management of Biliary Atresia in Hawai'i, 2009-2023.Hawai'i journal of health & social welfare · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Krupa R MysoreDepartment of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Baylor College of Medicine and Texas Children's Hospital, Houston, TX.
Benjamin L Shneider
Sanjiv Harpavat

Funding

Assessment of a Novel Newborn Screening Tool for Biliary AtresiaK23DK109207 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI HARPAVAT, SANJIV · 2017 to 2021
$901k
NIDDK NIH HHS K23 DK109207
6 · The paper itself

Abstract

Biliary atresia (BA) is the most common reason for pediatric liver transplant. BA's varied presentation, natural history, and treatment with the Kasai portoenterostomy have been well described; however, when BA starts relative to birth has not been clearly defined. In this review, we discuss laboratory, imaging, and clinical data which suggest that most if not all forms of BA may start before birth. This early onset has implications in terms of delivering treatments earlier and identifying possible factors underlying BA's etiology.

Indexed as

Neonatal ScreeningPrenatal DiagnosisAdultBiliary AtresiaFemaleHumansInfant, NewbornPregnancy

Identifiers

PMID31335837
PMCPMC6942669

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.