Evidence map›Paper›PMID 31335699›Full record

ArticleMedicine2019

Applicability of readout-segmented echoplanar diffusion weighted imaging for prostate MRI.

Susanne Hellms, Marcel Gutberlet, Matti Joonas Peperhove, Stefanie Pertschy, Christoph Henkenberens, Inga Peters, Frank Wacker, Katja Derlin

Abstract read
In one paragraph

Article in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Comparison of ZOOMit-DWI sequence and conventional DWI sequence in endometrial cancer.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Susanne HellmsInstitute for Diagnostic and Interventional Radiology.
Marcel GutberletInstitute for Diagnostic and Interventional Radiology.
Matti Joonas PeperhoveInstitute for Diagnostic and Interventional Radiology.
Stefanie PertschyInstitute for Diagnostic and Interventional Radiology.
Christoph HenkenberensInstitute for Radiation Therapy and Special Oncology.
Inga PetersClinic for Urology and urologic Oncology, Hannover Medical School, Hannover, Germany.
Frank WackerInstitute for Diagnostic and Interventional Radiology.
Katja DerlinInstitute for Diagnostic and Interventional Radiology.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate readout-segmented echoplanar (rsEPI) diffusion weighted imaging (DWI) for multiparametric (mp) magnetic resonance imaging (MRI) of the prostate compared to the established single-shot echoplanar imaging (ssEPI) sequence.One hundred ten consecutive patients with clinical suspicion of prostate cancer underwent mp prostate MRI using both, the ssEPI and the rsEPI DWI sequence. For an objective assessment, delineation of the prostate shape on both DWI sequences was compared to T2-weighted images by measuring organ diameters. Apparent diffusion coefficient (ADC) values, image contrast and contrast-to-noise ratio (CNR) were compared between the 2 sequences on a region-of-interest-based analysis. Diagnostic accuracy for quantitative ADC-values was calculated. Histopathology from MRI/ultrasound fusion-guided biopsy was used as reference standard. For a subjective assessment, 2 independent readers visually assessed image quality of both sequences using Likert-scales.Delineation of the prostate shape was more accurate with rsEPI compared to ssEPI. ADC values in target lesions were not significantly different but significantly higher in the surrounding normal prostatic tissue of the transition zone. CNR was comparable between ssEPI and rsEPI. Sensitivity and specificity were good for both sequences with 84/84% and 82/73% with a Youden selected cut-off of ADC = 0.971*10 mm/s for rsEPI and 1.017*10 mm/s for ssEPI. Anatomic artifacts were significantly less and SNR was lower on rsEPI compared to ssEPI in the subjective analysis.Delineation of the prostate shape was more accurate with rsEPI DWI than with ssEPI DWI with less anatomic artifacts and higher subjective SNR and image quality on rsEPI DW images. Diagnostic ability of quantitative ADC-values was not significantly different between the 2 sequences. Thus, rsEPI DWI might be more suitable for prostate MRI with regard to MRI-guided targeted biopsy and therapy planning.

Indexed as

ProstateProstatic NeoplasmsAgedComparative Effectiveness ResearchDiffusion Magnetic Resonance ImagingDimensional Measurement AccuracyEcho-Planar ImagingHumansImage-Guided BiopsyMaleMiddle AgedOrgan SizePatient Care PlanningReproducibility of Results

Identifiers

PMID31335699
PMCPMC6709253

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.