Evidence map›Paper›PMID 31335282›Full record

ArticleRadiology2019

Reproducibility and Changes in Vena Caval Blood Flow by Using 4D Flow MRI in Pulmonary Emphysema and Chronic Obstructive Pulmonary Disease (COPD): The Multi-Ethnic Study of Atherosclerosis (MESA) COPD Substudy.

Ozair Rahman, Michael Markl, Pallavi Balte, Haben Berhane, Carmen Blanken, Kenichiro Suwa, Stephen Dashnaw, Oliver Wieben, David A Bluemke, Martin R Prince and 9 more

Open access · greenAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Why 4D Flow MRI? Real Advantages.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2022
    Article
  7. Quality Control for 4D Flow MR Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2022
    Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors at 1 institution in 1 country.

Ozair RahmanFrom the Department of Radiology, Feinberg School of Medicine, Northwestern University, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611 (O.R., M.M., H.B., C.B., K.S., J.C.); Departments of Radiology (O.R., S.D., M.R.P., Y.S.), Medicine (P.B., Y.S., R.G.B.), and Epidemiology (R.G.B.), Columbia University Medical Center, New York, NY; Department of Radiology, NewYork-Presbyterian Hospital, New York, NY (O.R.); Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Ill (M.M.); Departments of Medical Physics (O.W.) and Radiology (D.A.B.), University of Wisconsin School of Medicine and Public Health, Madison, Wis; Division of Cardiology, Johns Hopkins University, Baltimore, Md (J.L., E.M., B.A.V.); Department of Radiology, Biomedical Engineering and Medicine, University of Iowa, Iowa City, Iowa (E.A.H.); and Departments of Radiology (A.S.G.) and Medicine (K.W.), University of California Los Angeles, Los Angeles, Calif.ORCID 0000-0002-0919-5604
Michael MarklFrom the Department of Radiology, Feinberg School of Medicine, Northwestern University, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611 (O.R., M.M., H.B., C.B., K.S., J.C.); Departments of Radiology (O.R., S.D., M.R.P., Y.S.), Medicine (P.B., Y.S., R.G.B.), and Epidemiology (R.G.B.), Columbia University Medical Center, New York, NY; Department of Radiology, NewYork-Presbyterian Hospital, New York, NY (O.R.); Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Ill (M.M.); Departments of Medical Physics (O.W.) and Radiology (D.A.B.), University of Wisconsin School of Medicine and Public Health, Madison, Wis; Division of Cardiology, Johns Hopkins University, Baltimore, Md (J.L., E.M., B.A.V.); Department of Radiology, Biomedical Engineering and Medicine, University of Iowa, Iowa City, Iowa (E.A.H.); and Departments of Radiology (A.S.G.) and Medicine (K.W.), University of California Los Angeles, Los Angeles, Calif.ORCID 0000-0002-7686-1128
Pallavi BalteFrom the Department of Radiology, Feinberg School of Medicine, Northwestern University, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611 (O.R., M.M., H.B., C.B., K.S., J.C.); Departments of Radiology (O.R., S.D., M.R.P., Y.S.), Medicine (P.B., Y.S., R.G.B.), and Epidemiology (R.G.B.), Columbia University Medical Center, New York, NY; Department of Radiology, NewYork-Presbyterian Hospital, New York, NY (O.R.); Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Ill (M.M.); Departments of Medical Physics (O.W.) and Radiology (D.A.B.), University of Wisconsin School of Medicine and Public Health, Madison, Wis; Division of Cardiology, Johns Hopkins University, Baltimore, Md (J.L., E.M., B.A.V.); Department of Radiology, Biomedical Engineering and Medicine, University of Iowa, Iowa City, Iowa (E.A.H.); and Departments of Radiology (A.S.G.) and Medicine (K.W.), University of California Los Angeles, Los Angeles, Calif.ORCID 0000-0001-5610-3744
Haben BerhaneFrom the Department of Radiology, Feinberg School of Medicine, Northwestern University, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611 (O.R., M.M., H.B., C.B., K.S., J.C.); Departments of Radiology (O.R., S.D., M.R.P., Y.S.), Medicine (P.B., Y.S., R.G.B.), and Epidemiology (R.G.B.), Columbia University Medical Center, New York, NY; Department of Radiology, NewYork-Presbyterian Hospital, New York, NY (O.R.); Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Ill (M.M.); Departments of Medical Physics (O.W.) and Radiology (D.A.B.), University of Wisconsin School of Medicine and Public Health, Madison, Wis; Division of Cardiology, Johns Hopkins University, Baltimore, Md (J.L., E.M., B.A.V.); Department of Radiology, Biomedical Engineering and Medicine, University of Iowa, Iowa City, Iowa (E.A.H.); and Departments of Radiology (A.S.G.) and Medicine (K.W.), University of California Los Angeles, Los Angeles, Calif.ORCID 0000-0002-1381-7373
Carmen BlankenFrom the Department of Radiology, Feinberg School of Medicine, Northwestern University, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611 (O.R., M.M., H.B., C.B., K.S., J.C.); Departments of Radiology (O.R., S.D., M.R.P., Y.S.), Medicine (P.B., Y.S., R.G.B.), and Epidemiology (R.G.B.), Columbia University Medical Center, New York, NY; Department of Radiology, NewYork-Presbyterian Hospital, New York, NY (O.R.); Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Ill (M.M.); Departments of Medical Physics (O.W.) and Radiology (D.A.B.), University of Wisconsin School of Medicine and Public Health, Madison, Wis; Division of Cardiology, Johns Hopkins University, Baltimore, Md (J.L., E.M., B.A.V.); Department of Radiology, Biomedical Engineering and Medicine, University of Iowa, Iowa City, Iowa (E.A.H.); and Departments of Radiology (A.S.G.) and Medicine (K.W.), University of California Los Angeles, Los Angeles, Calif.ORCID 0000-0002-3008-3236
Kenichiro SuwaFrom the Department of Radiology, Feinberg School of Medicine, Northwestern University, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611 (O.R., M.M., H.B., C.B., K.S., J.C.); Departments of Radiology (O.R., S.D., M.R.P., Y.S.), Medicine (P.B., Y.S., R.G.B.), and Epidemiology (R.G.B.), Columbia University Medical Center, New York, NY; Department of Radiology, NewYork-Presbyterian Hospital, New York, NY (O.R.); Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Ill (M.M.); Departments of Medical Physics (O.W.) and Radiology (D.A.B.), University of Wisconsin School of Medicine and Public Health, Madison, Wis; Division of Cardiology, Johns Hopkins University, Baltimore, Md (J.L., E.M., B.A.V.); Department of Radiology, Biomedical Engineering and Medicine, University of Iowa, Iowa City, Iowa (E.A.H.); and Departments of Radiology (A.S.G.) and Medicine (K.W.), University of California Los Angeles, Los Angeles, Calif.ORCID 0000-0001-6934-7932
Stephen DashnawFrom the Department of Radiology, Feinberg School of Medicine, Northwestern University, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611 (O.R., M.M., H.B., C.B., K.S., J.C.); Departments of Radiology (O.R., S.D., M.R.P., Y.S.), Medicine (P.B., Y.S., R.G.B.), and Epidemiology (R.G.B.), Columbia University Medical Center, New York, NY; Department of Radiology, NewYork-Presbyterian Hospital, New York, NY (O.R.); Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Ill (M.M.); Departments of Medical Physics (O.W.) and Radiology (D.A.B.), University of Wisconsin School of Medicine and Public Health, Madison, Wis; Division of Cardiology, Johns Hopkins University, Baltimore, Md (J.L., E.M., B.A.V.); Department of Radiology, Biomedical Engineering and Medicine, University of Iowa, Iowa City, Iowa (E.A.H.); and Departments of Radiology (A.S.G.) and Medicine (K.W.), University of California Los Angeles, Los Angeles, Calif.ORCID 0000-0003-1531-2827
Oliver WiebenFrom the Department of Radiology, Feinberg School of Medicine, Northwestern University, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611 (O.R., M.M., H.B., C.B., K.S., J.C.); Departments of Radiology (O.R., S.D., M.R.P., Y.S.), Medicine (P.B., Y.S., R.G.B.), and Epidemiology (R.G.B.), Columbia University Medical Center, New York, NY; Department of Radiology, NewYork-Presbyterian Hospital, New York, NY (O.R.); Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Ill (M.M.); Departments of Medical Physics (O.W.) and Radiology (D.A.B.), University of Wisconsin School of Medicine and Public Health, Madison, Wis; Division of Cardiology, Johns Hopkins University, Baltimore, Md (J.L., E.M., B.A.V.); Department of Radiology, Biomedical Engineering and Medicine, University of Iowa, Iowa City, Iowa (E.A.H.); and Departments of Radiology (A.S.G.) and Medicine (K.W.), University of California Los Angeles, Los Angeles, Calif.
David A BluemkeFrom the Department of Radiology, Feinberg School of Medicine, Northwestern University, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611 (O.R., M.M., H.B., C.B., K.S., J.C.); Departments of Radiology (O.R., S.D., M.R.P., Y.S.), Medicine (P.B., Y.S., R.G.B.), and Epidemiology (R.G.B.), Columbia University Medical Center, New York, NY; Department of Radiology, NewYork-Presbyterian Hospital, New York, NY (O.R.); Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Ill (M.M.); Departments of Medical Physics (O.W.) and Radiology (D.A.B.), University of Wisconsin School of Medicine and Public Health, Madison, Wis; Division of Cardiology, Johns Hopkins University, Baltimore, Md (J.L., E.M., B.A.V.); Department of Radiology, Biomedical Engineering and Medicine, University of Iowa, Iowa City, Iowa (E.A.H.); and Departments of Radiology (A.S.G.) and Medicine (K.W.), University of California Los Angeles, Los Angeles, Calif.
Martin R PrinceFrom the Department of Radiology, Feinberg School of Medicine, Northwestern University, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611 (O.R., M.M., H.B., C.B., K.S., J.C.); Departments of Radiology (O.R., S.D., M.R.P., Y.S.), Medicine (P.B., Y.S., R.G.B.), and Epidemiology (R.G.B.), Columbia University Medical Center, New York, NY; Department of Radiology, NewYork-Presbyterian Hospital, New York, NY (O.R.); Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Ill (M.M.); Departments of Medical Physics (O.W.) and Radiology (D.A.B.), University of Wisconsin School of Medicine and Public Health, Madison, Wis; Division of Cardiology, Johns Hopkins University, Baltimore, Md (J.L., E.M., B.A.V.); Department of Radiology, Biomedical Engineering and Medicine, University of Iowa, Iowa City, Iowa (E.A.H.); and Departments of Radiology (A.S.G.) and Medicine (K.W.), University of California Los Angeles, Los Angeles, Calif.ORCID 0000-0002-9883-0584
Joao LimaFrom the Department of Radiology, Feinberg School of Medicine, Northwestern University, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611 (O.R., M.M., H.B., C.B., K.S., J.C.); Departments of Radiology (O.R., S.D., M.R.P., Y.S.), Medicine (P.B., Y.S., R.G.B.), and Epidemiology (R.G.B.), Columbia University Medical Center, New York, NY; Department of Radiology, NewYork-Presbyterian Hospital, New York, NY (O.R.); Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Ill (M.M.); Departments of Medical Physics (O.W.) and Radiology (D.A.B.), University of Wisconsin School of Medicine and Public Health, Madison, Wis; Division of Cardiology, Johns Hopkins University, Baltimore, Md (J.L., E.M., B.A.V.); Department of Radiology, Biomedical Engineering and Medicine, University of Iowa, Iowa City, Iowa (E.A.H.); and Departments of Radiology (A.S.G.) and Medicine (K.W.), University of California Los Angeles, Los Angeles, Calif.ORCID 0000-0001-8756-6995
Erin MichosFrom the Department of Radiology, Feinberg School of Medicine, Northwestern University, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611 (O.R., M.M., H.B., C.B., K.S., J.C.); Departments of Radiology (O.R., S.D., M.R.P., Y.S.), Medicine (P.B., Y.S., R.G.B.), and Epidemiology (R.G.B.), Columbia University Medical Center, New York, NY; Department of Radiology, NewYork-Presbyterian Hospital, New York, NY (O.R.); Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Ill (M.M.); Departments of Medical Physics (O.W.) and Radiology (D.A.B.), University of Wisconsin School of Medicine and Public Health, Madison, Wis; Division of Cardiology, Johns Hopkins University, Baltimore, Md (J.L., E.M., B.A.V.); Department of Radiology, Biomedical Engineering and Medicine, University of Iowa, Iowa City, Iowa (E.A.H.); and Departments of Radiology (A.S.G.) and Medicine (K.W.), University of California Los Angeles, Los Angeles, Calif.ORCID 0000-0002-5547-5084
Bharath Ambale-VenkateshFrom the Department of Radiology, Feinberg School of Medicine, Northwestern University, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611 (O.R., M.M., H.B., C.B., K.S., J.C.); Departments of Radiology (O.R., S.D., M.R.P., Y.S.), Medicine (P.B., Y.S., R.G.B.), and Epidemiology (R.G.B.), Columbia University Medical Center, New York, NY; Department of Radiology, NewYork-Presbyterian Hospital, New York, NY (O.R.); Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Ill (M.M.); Departments of Medical Physics (O.W.) and Radiology (D.A.B.), University of Wisconsin School of Medicine and Public Health, Madison, Wis; Division of Cardiology, Johns Hopkins University, Baltimore, Md (J.L., E.M., B.A.V.); Department of Radiology, Biomedical Engineering and Medicine, University of Iowa, Iowa City, Iowa (E.A.H.); and Departments of Radiology (A.S.G.) and Medicine (K.W.), University of California Los Angeles, Los Angeles, Calif.ORCID 0000-0002-2330-2373
Eric A HoffmanFrom the Department of Radiology, Feinberg School of Medicine, Northwestern University, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611 (O.R., M.M., H.B., C.B., K.S., J.C.); Departments of Radiology (O.R., S.D., M.R.P., Y.S.), Medicine (P.B., Y.S., R.G.B.), and Epidemiology (R.G.B.), Columbia University Medical Center, New York, NY; Department of Radiology, NewYork-Presbyterian Hospital, New York, NY (O.R.); Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Ill (M.M.); Departments of Medical Physics (O.W.) and Radiology (D.A.B.), University of Wisconsin School of Medicine and Public Health, Madison, Wis; Division of Cardiology, Johns Hopkins University, Baltimore, Md (J.L., E.M., B.A.V.); Department of Radiology, Biomedical Engineering and Medicine, University of Iowa, Iowa City, Iowa (E.A.H.); and Departments of Radiology (A.S.G.) and Medicine (K.W.), University of California Los Angeles, Los Angeles, Calif.ORCID 0000-0001-8456-9437
Antoinette S GomesFrom the Department of Radiology, Feinberg School of Medicine, Northwestern University, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611 (O.R., M.M., H.B., C.B., K.S., J.C.); Departments of Radiology (O.R., S.D., M.R.P., Y.S.), Medicine (P.B., Y.S., R.G.B.), and Epidemiology (R.G.B.), Columbia University Medical Center, New York, NY; Department of Radiology, NewYork-Presbyterian Hospital, New York, NY (O.R.); Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Ill (M.M.); Departments of Medical Physics (O.W.) and Radiology (D.A.B.), University of Wisconsin School of Medicine and Public Health, Madison, Wis; Division of Cardiology, Johns Hopkins University, Baltimore, Md (J.L., E.M., B.A.V.); Department of Radiology, Biomedical Engineering and Medicine, University of Iowa, Iowa City, Iowa (E.A.H.); and Departments of Radiology (A.S.G.) and Medicine (K.W.), University of California Los Angeles, Los Angeles, Calif.ORCID 0000-0001-8916-8341
Karol WatsonFrom the Department of Radiology, Feinberg School of Medicine, Northwestern University, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611 (O.R., M.M., H.B., C.B., K.S., J.C.); Departments of Radiology (O.R., S.D., M.R.P., Y.S.), Medicine (P.B., Y.S., R.G.B.), and Epidemiology (R.G.B.), Columbia University Medical Center, New York, NY; Department of Radiology, NewYork-Presbyterian Hospital, New York, NY (O.R.); Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Ill (M.M.); Departments of Medical Physics (O.W.) and Radiology (D.A.B.), University of Wisconsin School of Medicine and Public Health, Madison, Wis; Division of Cardiology, Johns Hopkins University, Baltimore, Md (J.L., E.M., B.A.V.); Department of Radiology, Biomedical Engineering and Medicine, University of Iowa, Iowa City, Iowa (E.A.H.); and Departments of Radiology (A.S.G.) and Medicine (K.W.), University of California Los Angeles, Los Angeles, Calif.
Yanping SunFrom the Department of Radiology, Feinberg School of Medicine, Northwestern University, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611 (O.R., M.M., H.B., C.B., K.S., J.C.); Departments of Radiology (O.R., S.D., M.R.P., Y.S.), Medicine (P.B., Y.S., R.G.B.), and Epidemiology (R.G.B.), Columbia University Medical Center, New York, NY; Department of Radiology, NewYork-Presbyterian Hospital, New York, NY (O.R.); Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Ill (M.M.); Departments of Medical Physics (O.W.) and Radiology (D.A.B.), University of Wisconsin School of Medicine and Public Health, Madison, Wis; Division of Cardiology, Johns Hopkins University, Baltimore, Md (J.L., E.M., B.A.V.); Department of Radiology, Biomedical Engineering and Medicine, University of Iowa, Iowa City, Iowa (E.A.H.); and Departments of Radiology (A.S.G.) and Medicine (K.W.), University of California Los Angeles, Los Angeles, Calif.
James CarrFrom the Department of Radiology, Feinberg School of Medicine, Northwestern University, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611 (O.R., M.M., H.B., C.B., K.S., J.C.); Departments of Radiology (O.R., S.D., M.R.P., Y.S.), Medicine (P.B., Y.S., R.G.B.), and Epidemiology (R.G.B.), Columbia University Medical Center, New York, NY; Department of Radiology, NewYork-Presbyterian Hospital, New York, NY (O.R.); Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Ill (M.M.); Departments of Medical Physics (O.W.) and Radiology (D.A.B.), University of Wisconsin School of Medicine and Public Health, Madison, Wis; Division of Cardiology, Johns Hopkins University, Baltimore, Md (J.L., E.M., B.A.V.); Department of Radiology, Biomedical Engineering and Medicine, University of Iowa, Iowa City, Iowa (E.A.H.); and Departments of Radiology (A.S.G.) and Medicine (K.W.), University of California Los Angeles, Los Angeles, Calif.
R Graham BarrFrom the Department of Radiology, Feinberg School of Medicine, Northwestern University, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611 (O.R., M.M., H.B., C.B., K.S., J.C.); Departments of Radiology (O.R., S.D., M.R.P., Y.S.), Medicine (P.B., Y.S., R.G.B.), and Epidemiology (R.G.B.), Columbia University Medical Center, New York, NY; Department of Radiology, NewYork-Presbyterian Hospital, New York, NY (O.R.); Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Ill (M.M.); Departments of Medical Physics (O.W.) and Radiology (D.A.B.), University of Wisconsin School of Medicine and Public Health, Madison, Wis; Division of Cardiology, Johns Hopkins University, Baltimore, Md (J.L., E.M., B.A.V.); Department of Radiology, Biomedical Engineering and Medicine, University of Iowa, Iowa City, Iowa (E.A.H.); and Departments of Radiology (A.S.G.) and Medicine (K.W.), University of California Los Angeles, Los Angeles, Calif.
Northwestern University · US

Funding

Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024156 · NCRR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2006 to 2011
$53.0M
Vector Core-Core 2P30DK054759 · NIDDK · UNIVERSITY OF IOWA · PI Alejandro Antonio Pezzulo · 1998 to 2026
$30.5M
Clinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2M
Pulmonary microvascular perfusion in the Multi-Ethnic Study of AtherosclerosisR01HL077612 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI R Graham BARR · 2004 to 2026
$18.8M
Pulmonary Vascular Changes in Early Chronic Obstructive Pulmonary Disease (COPD)R01HL093081 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI R Graham BARR · 2008 to 2026
$17.2M
Multi-center Structural & Functional Quantitative CT Pulmonary PhenotypingR01HL112986 · NHLBI · UNIVERSITY OF IOWA · PI HOFFMAN, ERIC ALFRED · 2012 to 2016
$4.6M
Ultra-low Dose, High Speed, High Resolution, Multispectral, Multi-Source MDCT ScaS10OD018526 · OD · UNIVERSITY OF IOWA · PI HOFFMAN, ERIC ALFRED · 2015 to 2015
$2.0M
Cigarette Smoke and Susceptibility to Influenza InfectionR01HL095163 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JASPERS, ILONA, NOAH, TERRY L · 2009 to 2013
$2.0M
Adjunctive Use of Apyrase to Fibrinolytic TherapyR44HL095169 · NHLBI · APT THERAPEUTICS, INC. · PI CHEN, RIDONG · 2012 to 2013
$1.3M
SUBCLINICAL CARDIOVASCULAR DISEASE STUDYN01HC095166 · HC · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI TRACY, RUSSELL P · 1999 to 2001
$758k
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY-FIELD CENTERN01HC095162 · HC · JOHNS HOPKINS UNIVERSITY · PI SZKLO, MOYSES A · 1999 to 2000
$694k
NCATS NIH HHS UL1 TR000040NCATS NIH HHS UL1 TR001079NCRR NIH HHS UL1 RR024156NHLBI NIH HHS N01 HC095159NHLBI NIH HHS N01 HC095160NHLBI NIH HHS N01 HC095161NHLBI NIH HHS N01 HC095162NHLBI NIH HHS N01 HC095163NHLBI NIH HHS N01 HC095164NHLBI NIH HHS N01 HC095165NHLBI NIH HHS N01 HC095166NHLBI NIH HHS N01 HC095167NHLBI NIH HHS N01 HC095168NHLBI NIH HHS N01 HC095169NHLBI NIH HHS R01 HL077612NHLBI NIH HHS R01 HL093081NHLBI NIH HHS R01 HL112986NIDDK NIH HHS P30 DK054759NIH HHS S10 OD018526
6 · The paper itself

Abstract

BackgroundChronic obstructive pulmonary disease (COPD) is associated with hemodynamic changes in the pulmonary vasculature. However, cardiac effects are not fully understood and vary by phenotype of chronic lower respiratory disease.PurposeTo use four-dimensional (4D) flow MRI for comprehensive assessment of the right-sided cardiovascular system, assess its interrater and intraobserver reproducibility, and examine associations with venous return to the right heart in individuals with chronic COPD and emphysema.Materials and MethodsThe Multi-Ethnic Study of Atherosclerosis COPD substudy prospectively recruited participants who smoked and who had COPD and nested control participants from population-based samples. Electrocardiography and respiratory gated 4D flow 1.5-T MRI was performed at three sites with full volumetric coverage of the thoracic vessels in 2014-2017 with postbronchodilator spirometry and inspiratory chest CT to quantify percent emphysema. Net flow, peak velocity, retrograde flow, and retrograde fraction were measured on 14 analysis planes. Interrater reproducibility was assessed by two independent observers, and the principle of conservation of mass was employed to evaluate the internal consistency of flow measures. Partial correlation coefficients were adjusted for age, sex, race/ethnicity, height, weight, and smoking status.ResultsAmong 70 participants (29 participants with COPD [mean age, 73.5 years ± 8.1 {standard deviation}; 20 men] and 41 control participants [mean age, 71.0 years ± 6.1; 22 men]), the interrater reproducibility of the 4D flow MRI measures was good to excellent (intraclass correlation coefficient range, 0.73-0.98), as was the internal consistency. There were no statistically significant differences in venous flow parameters according to COPD severity (

Indexed as

AgedAtherosclerosisBlood Flow VelocityEthnicityFemaleHumansImaging, Three-DimensionalLungMagnetic Resonance ImagingMaleProspective StudiesPulmonary Disease, Chronic ObstructivePulmonary EmphysemaReproducibility of ResultsVenae Cavae

Identifiers

PMID31335282
PMCPMC6736177
OpenAlexW2963408525

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