ArticleJournal of athletic training2019
A 14-Day Recovery and Physical Activity Levels After an Ankle Sprain in Mice.
Article in Journal of athletic training, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed, 6 citations in OpenAlex.
- Corticospinal tract alterations after ankle sprain in adolescence: Insights from the mouse model.Sports medicine and health science · 2025Article
- Effects of chronic ankle instability after grade I ankle sprain on the post-traumatic osteoarthritis.Arthritis research & therapy · 2024Article
- Mouse model of subtalar post-traumatic osteoarthritis caused by subtalar joint instability.Journal of orthopaedic surgery and research · 2022Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextResearch is needed to find ways of improving physical activity after a lateral ankle sprain.
objectiveTo investigate the effects of a prolonged rest period on lifelong activity after a surgically induced ankle sprain.
designControlled laboratory study.
settingResearch laboratory. PATIENTS OR OTHER
participantsA total of 18 male CBA/J mice (age at surgery = 7 weeks). MAIN OUTCOME MEASURE(S): We transected the anterior talofibular ligament and calcaneofibular ligament of the right hindlimb. Each mouse was placed in a separate cage and randomized into 1 of 3 groups of 6 mice each. A running wheel was placed in each cage at 3 days, 7 days, or 14 days after surgery. Physical activity was measured daily. Daily duration (ie, time spent on the wheel), distance, and running speed were examined using analysis of variance (group × age) with repeated measures at 15-week periods to approximate the first 3 quartiles of the lifespan.
resultsFrom weeks 3 to 15 after surgery, we observed no differences in duration, distance, or running speed among groups (
conclusionsOur findings suggest that the longer recovery period of 14 days can increase activity levels throughout the lifespan after a severe ankle sprain. Rest after an ankle injury is critical to restoring physical activity levels across the lifespan. Rest and time away from exercise after an ankle sprain may be necessary to restore physical activity to normal, uninjured levels.
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Registered trials
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