Observational studyColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland2020
Urinary dysfunction in patients with rectal cancer: a prospective cohort study.
Observational study in Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- The Frequency of Urination Dysfunction in Patients Operated on for Rectal Cancer: A Systematic Review with Meta-Analyses.Current oncology (Toronto, Ont.) · 2024Pooled it
- Urinary and sexual function after robotic and laparoscopic rectal cancer surgery: a systematic review and meta-analysis.Journal of robotic surgery · 2024Pooled it
- Developing a multivariable prediction model of global health-related quality of life in patients treated for rectal cancer: a prospective study in five countries.International journal of colorectal disease · 2024Trial
- Symptom burden among long-term survivors of young adult cancer: a report from the Project Milestones cohort.Journal of cancer survivorship : research and practice · 2026Article
- Risk factors and development of a nomogram prediction model for urinary dysfunction after laparoscopic radical surgery for rectal cancer.Frontiers in surgery · 2026Article
- Postoperative Morbidity Is Not Associated with a Worse Mid-Term Quality of Life After Colorectal Surgery for Colorectal Carcinoma.Journal of clinical medicine · 2025Article
- Functional outcomes in rectal cancer patients treated with immunotherapy and neoadjuvant therapy: a retrospective analysis.Langenbeck's archives of surgery · 2025Article
- Predictive Risk Factors for Low Anterior Resection Syndrome (LARS) in Rectal Cancer-An Observational Cohort Study.Journal of clinical medicine · 2025Article
- Watch-and-Wait Approach Following Neoadjuvant Chemo-Radiotherapy for Locally Advanced Rectal Cancer: A Retrospective Single-Center Cohort Study.Journal of surgical oncology · 2025Article
- Neoadjuvant Treatment in Rectal Cancer.South Asian journal of cancer · 2024Review
- Intraoperative pelvic neuromonitoring based on bioimpedance signals: a new method analyzed on 30 patients.Langenbeck's archives of surgery · 2024Article
- The Management of a Urinary Bladder Leak in a Patient with Radiation Cystitis.Radiology case reports · 2024Article
- Review
- Long-term survival and functional outcomes of laparoscopic surgery for clinical stage I ultra-low rectal cancers located within 5 cm of the anal verge: A prospective phase II trial (Ultimate trial).Annals of surgery · 2024Article
- Automatic muscle impedance and nerve analyzer (AMINA) as a novel approach for classifying bioimpedance signals in intraoperative pelvic neuromonitoring.Scientific reports · 2024Article
- Article
- Multi-Disciplinary Management in Rectal Cancer Survivorship: A Clinical Practice Review.Journal of gastrointestinal cancer · 2023Review
- Age-related differences in the occurrence, severity, and distress of symptoms in older patients at the initiation of chemotherapy.BMC geriatrics · 2023Article
- Renal Dysfunction after Rectal Cancer Surgery: A Long-term Observational Study.Journal of the anus, rectum and colon · 2023Article
- Establishment of a nurse-led clinic for late complications after colorectal and anal cancer surgery: a descriptive study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimUrinary dysfunction is one of many complications after treatment for rectal cancer. The aim of this study was to evaluate the prevalence of patient-reported urinary dysfunction at the time of diagnosis and at 1-year follow-up and to assess the risk factors linked to urinary incontinence.
methodPatients with newly diagnosed rectal cancer were included in the QoLiRECT study between 2012 and 2015. Questionnaires from the time of diagnosis and 1-year follow-up were analysed, with 1085 and 916 patients, respectively, eligible for analysis. Regression analyses were made to investigate possible risk factors for incontinence. The patient cohort was also compared with a cohort from the Swedish general population.
resultsAt baseline, the prevalence of urinary dysfunction (14% of women, 8% of men) was similar to that in the general population. At 1-year follow-up, 20% of patients experienced urinary incontinence (29% of women, 14% of men). Emptying difficulties were experienced by 46% (41% of women, 49% of men) and urgency by 58% across both sexes. Abdominoperineal excision and urinary dysfunction at baseline were found to be independent risk factors for incontinence at 1-year follow-up. Among patients who were continent at baseline, risk factors were female sex, physical inactivity at baseline, comorbidity and abdominoperineal excision.
conclusionUrinary dysfunction is frequent among patients with rectal cancer, with up to a two-fold increase in symptoms 1 year after diagnosis. Unfortunately, few factors are modifiable and these results stress the importance of informing patients of possible outcomes related to urinary dysfunction after treatment for rectal cancer.
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