Evidence map›Paper›PMID 31334300›Full record

ArticleOpen forum infectious diseases2019

Transfusion-Transmitted Malaria: A Systematic Review and Meta-analysis.

Ehsan Ahmadpour, Masoud Foroutan-Rad, Hamidreza Majidiani, Sirous Mehrani Moghaddam, Kareem Hatam-Nahavandi, Seyed-Abdollah Hosseini, Mohammad Taghi Rahimi, Aleksandra Barac, Salvatore Rubino, Mehdi Zarean and 2 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 29 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 4 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 4 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Transfusion-transmittedThe Lancet regional health. Southeast Asia · 2025
    Review
  11. Article
  12. Malaria.The New England journal of medicine · 2025
    Review
  13. Review
  14. Biopreserving Pathogens: Promise & Peril.The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics · 2024
    Article
  15. Article
  16. Article
  17. Criminal and Civil Responsibility of the Donor in a Case of Transmission of Malaria by a Blood Transfusion in a Nonendemic Country.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2022
    Article
  18. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2022
    Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 3 countries.

Ehsan AhmadpourInfectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Masoud Foroutan-RadDepartment of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Hamidreza MajidianiDepartment of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Sirous Mehrani MoghaddamImmunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Kareem Hatam-NahavandiIranshahr University of Medical Sciences, Iranshahr, Iran.
Seyed-Abdollah HosseiniToxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Mohammad Taghi RahimiSchool of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran.
Aleksandra BaracClinic for Infectious and Tropical Diseases, Clinical Centre of Serbia, Belgrade, Serbia.
Salvatore RubinoDepartment of Biomedical Sciences, University of Sassari, Sardinia, Italy.
Mehdi ZareanDepartment of Parasitology and Mycology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Alexander G MathioudakisDivision of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
Muge CevikDivision of Infection and Global Health Research, School of Medicine, University of St Andrews, Fife, Scotland, UK.
Tabriz University of Medical Sciences · IRTarbiat Modares University · IRIranshahr University · IRMashhad University of Medical Sciences · IRMazandaran University of Medical Sciences · IRShahroud University of Medical Sciences · IRUniversity of Manchester · GBUniversity of Sassari · ITUniversity of St Andrews · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalaria transmission through blood transfusion is an accidental but preventable cause of malaria infection and is increasingly becoming a matter of concern for blood transfusion services. This systematic review was conducted to provide a summary of evidence about the prevalence of

methodsPRISMA guidelines were followed. Scopus, PubMed, Science Direct, and EMBASE were searched from 1982 to October 10, 2017. All peer-reviewed original research articles describing the prevalence of malaria parasitemia in blood donors with different diagnostic methods were included. The random-effects model was applied to assess the effects of heterogeneity among the selected studies. Incoherence and heterogeneity between studies were quantified by

resultsSeventy-one studies from 21 countries, 5 continents, were included in the present systematic review. The median prevalence of malaria parasitemia among 984 975 asymptomatic healthy blood donors was 10.54%, 5.36%, and 0.38% by microscopy, molecular methods (polymerase chain reaction), and rapid diagnostic tests, respectively. The most commonly detected

conclusionsThis systematic review demonstrates that compared with other transfusion-linked infections, that is, HIV, HCV, and HBV, transfusion-transmitted malaria is one of the most significant transfusion-associated infections especially in Sub-Saharan Africa. Future work must aim to understand the clinical significance of transfusion-transmitted malaria in malaria-endemic settings.

Indexed as

blood donorPlasmodiumsystematic reviewtransfusion-associated infectionstransfusion medicine

Identifiers

PMID31334300
PMCPMC6634438
OpenAlexW2949935442

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.