ArticleFrontiers in veterinary science2019
Pharmaceutical Prescription in Canine Acute Diarrhoea: A Longitudinal Electronic Health Record Analysis of First Opinion Veterinary Practices.
Article in Frontiers in veterinary science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.
- Efficacy of probiotic, prebiotic, synbiotic and postbiotic supplementation on gastrointestinal health in cats: systematic review and meta-analysis.The Journal of small animal practice · 2025Pooled it
- Probiotic Strains from Canine Milk Support Gastrointestinal Health in Weaning Labrador Retriever Puppies.Animals : an open access journal from MDPI · 2026Article
- Beneficial effects of a prebiotic-postbiotic supplement on digestive health and fecal microbiota in dogs and cats.Frontiers in veterinary science · 2026Article
- Understanding the rationale for metronidazole use in dogs and cats.The Journal of small animal practice · 2025Article
- Article
- Epidemiology and clinical management of acute diarrhoea in dogs under primary veterinary care in the UK.PloS one · 2025Article
- Influencing attitudes towards antimicrobial use and resistance in companion animals-the impact on pet owners of a short animation in a randomized controlled trial.JAC-antimicrobial resistance · 2024Article
- The Effect of Metronidazole versus a Synbiotic on Clinical Course and Core Intestinal Microbiota in Dogs with Acute Diarrhea.Veterinary sciences · 2024Article
- How low can you go? Antibiotic use in Swedish dogs with gastroenteritis.Frontiers in veterinary science · 2024Article
- Prevalence and appropriateness of omeprazole prescription in dogs at a veterinary teaching hospital before and after the publication of the ACVIM consensus statement on the rational administration of gastrointestinal protectants.Frontiers in veterinary science · 2024Article
- Patient weight has diverse effects on the prescribing of different antibiotics to dogs.Frontiers in veterinary science · 2024Article
- Dog Owners' Attitude toward Veterinary Antibiotic Use and Antibiotic Resistance with a Focus on Canine Diarrhea Management.Animals : an open access journal from MDPI · 2023Article
- Effects of a milk oligosaccharide biosimilar on fecal characteristics, microbiota, and bile acid, calprotectin, and immunoglobulin concentrations of healthy adult dogs treated with metronidazole.Journal of animal science · 2023Article
- A mixed-methods approach utilising electronic health records to examine antimicrobial prescription surrounding gastrointestinal clinical presentations in dogs and cats.Frontiers in veterinary science · 2023Article
- Article
- A quarterly Survey of antibiotic prescribing in small animal and equine practices-Minnesota and North Dakota, 2020.Zoonoses and public health · 2022Article
- Monitoring antimicrobial usage in companion animals: exploring the use of the Danish VetStat database.Acta veterinaria Scandinavica · 2022Article
- Gut microbiota development in the growing dog: A dynamic process influenced by maternal, environmental and host factors.Frontiers in veterinary science · 2022Review
- Patterns of antimicrobial drug use in veterinary primary care and specialty practice: A 6-year multi-institution study.Journal of veterinary internal medicine · 2021Article
- A randomised controlled trial to reduce highest priority critically important antimicrobial prescription in companion animals.Nature communications · 2021Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
Canine acute diarrhoea is frequently observed in first opinion practice, though little is known about commonly used diagnostic or therapeutic management plans, including use of antimicrobials. This retrospective observational study utilised electronic health records augmented with practitioner-completed questionnaires from 3,189 cases (3,159 dogs) collected from 179 volunteer veterinary practices between April 2014 and January 2017. We used multivariable analysis to explore factors potentially associated with pharmaceutical agent prescription, and resolution of clinical signs by 10 days post-initial presentation. Use of bacteriological and/or parasitological diagnostic tests were uncommon (3.2% of cases, 95% confidence interval, CI, 2.4-4.0), though systemic antimicrobials were the most commonly prescribed pharmaceutical agents (49.7% of cases, 95% CI 46.1-53.2). Such prescription was associated with haemorrhagic diarrhoea (odds ratio, OR, 4.1; 95% CI 3.4-5.0), body temperature in excess of 39.0°C, or moderate/severe cases (OR 1.3, 95% CI 1.1-1.7). Gastrointestinal agents (e.g., antacids) were prescribed to 37.7% of cases (95% CI 35.4-39.9), and were most frequently prescribed to vomiting dogs regardless of presence (OR 46.4, 95% CI 19.4-110.8) or absence of blood (OR 17.1, 95% CI 13.4-21.9). Endoparasiticides/endectocides were prescribed to 7.8% of cases (95% CI 6.8-9.0), such prescription being less frequent for moderate/severe cases (OR 0.5, 95% CI 0.4-0.7), though more frequent when weight loss was recorded (OR 3.4, 95% CI 1.3-9.0). Gastrointestinal nutraceuticals (e.g., probiotics) were dispensed to 60.8% of cases (95% CI 57.1-64.6), these cases less frequently presenting with moderate/severe clinical signs (OR 0.6, 95% CI 0.5-0.8). Nearly a quarter of cases were judged lost to follow-up (
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