Evidence map›Paper›PMID 31334171›Full record

ArticleJournal of family medicine and primary care2019

Cryptococcal meningitis: An under-reported disease from the hills of Uttarakhand: A hospital-based cross-sectional study.

Aroop Mohanty, Mohit Bhatia, Ankita Kabi, Kuhu Chatterjee, Neelam Kaistha, Balram Ji Omar, Puneet K Gupta, Pratima Gupta

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Article in Journal of family medicine and primary care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Aroop MohantyDepartment of Microbiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Mohit BhatiaDepartment of Microbiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Ankita KabiDepartment of Emergency Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Kuhu ChatterjeeDepartment of Microbiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Neelam KaisthaDepartment of Microbiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Balram Ji OmarDepartment of Microbiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Puneet K GuptaDepartment of Microbiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Pratima GuptaDepartment of Microbiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCryptococcal meningitis is a fatal opportunistic neuroinfection and an AIDS defining illness. It can also occur in non-HIV patients who are immunodefecient due to chronic glucocorticoid use, organ transplantation, malignancy and sarcodiosis. MATERIALS AND

methodsA cross-sectional study was conducted in a tertiary care hospital from July to December 2018. CSF samples of 364 patients were received by Microbiology laboratory during this period for the purpose of aerobic bacterial, fungal and TB culture, respectively. All samples were subjected to examination by direct wet mount, Gram stain and India ink preparation. Ziehl Neelsen staining, solid culture for

resultsOut of 364 CSF samples received, 288 were sterile after 48 hours of aerobic incubation. Bacterial isolates,

conclusionCryptococcal meningitis is a rapidly fatal condition which requires a high index of suspicion and calls for a collective effort from family physicians and diagnosticians alike. This disease is under-reported from Uttarakhand and therefore calls for further research from this region.

Indexed as

Amphotericin Bcryptococcal meningitisMALDI-TOF

Identifiers

PMID31334171
PMCPMC6618182

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