Evidence map›Paper›PMID 31333841›Full record

ArticleJournal of animal science and biotechnology2019

Meclofenamic acid represses spermatogonial proliferation through modulating m

Tao Huang, Jiayin Guo, Yinghua Lv, Yi Zheng, Tongying Feng, Qiang Gao, Wenxian Zeng

Open access · goldAbstract read
In one paragraph

Article in Journal of animal science and biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Transcriptome Studies Reveal theAnimals : an open access journal from MDPI · 2023
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Lipid metabolism and mJournal of animal science and biotechnology · 2022
    Article
  12. FTO protects human granulosa cells from chemotherapy-induced cytotoxicity.Reproductive biology and endocrinology : RB&E · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Epigenetic regulations in mammalian spermatogenesis: RNA-mCellular and molecular life sciences : CMLS · 2021
    Review
  17. Review
  18. Article
  19. The role of mCell death & disease · 2020
    Review
  20. Role of mEpigenomes · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Tao HuangKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, 712100 Shaanxi China.
Jiayin GuoKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, 712100 Shaanxi China.
Yinghua LvKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, 712100 Shaanxi China.
Yi ZhengKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, 712100 Shaanxi China.
Tongying FengKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, 712100 Shaanxi China.
Qiang GaoKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, 712100 Shaanxi China.
Wenxian ZengKey Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, 712100 Shaanxi China.ORCID 0000-0002-2912-8943
North West Agriculture and Forestry University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundN6-Methyladenosine (m

methodsMouse GC-1 spg cells were treated with the ester form of meclofenamic acid (MA2) to inhibit the demethylase activity of FTO. The cellular m

resultsMA2 significantly increased the cellular m

conclusionMA2 affected CDKs expression through the m

Indexed as

Cell cycleFTOMeclofenamic acidN6-methyladenosineSpermatogonial proliferation

Identifiers

PMID31333841
PMCPMC6621992
OpenAlexW2960813577

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.