Evidence map›Paper›PMID 31333682›Full record

ArticleFrontiers in immunology2019

Route of Vaccine Administration Influences the Impact of Fms-Like Tyrosine Kinase 3 Ligand (Flt3L) on Chlamydial-Specific Protective Immune Responses.

Roshan Pais, Yusuf Omosun, Joseph U Igietseme, Kohtaro Fujihashi, Francis O Eko

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. A VCG-Based MultiepitopeBiomedicines · 2025
    Article
  3. Article
  4. Article
  5. Heterologous Display ofMembranes · 2023
    Article
  6. Article
  7. Expert review of vaccines · 2021
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Roshan PaisDepartment of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, GA, United States.
Yusuf OmosunDepartment of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, GA, United States.
Joseph U IgietsemeMolecular Pathogenesis Laboratory, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Kohtaro FujihashiDepartment of Pediatric Dentistry, Institute of Oral Health Research, University of Alabama at Birmingham, Birmingham, AL, United States.
Francis O EkoDepartment of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, GA, United States.
Morehouse School of Medicine · USCenters for Disease Control and Prevention · USUniversity of Alabama at Birmingham · US

Funding

LYMPHOEPITHELIAL INTERACTION DURING CHLAMYDIAL INFECTIONR01AI041231 · NIAID · MOREHOUSE SCHOOL OF MEDICINE · PI EKO, FRANCIS O. · 1996 to 2014
$3.8M
IMMUNITY TO CHLAMYDIA ABORTUSR01AI126897 · NIAID · MOREHOUSE SCHOOL OF MEDICINE · PI EKO, FRANCIS O. · 2016 to 2019
$1.7M
RENOV OF MEDICAL SCI &EDUCATION BLDGS: RETINAL CELLSC06RR018386 · NCRR · MOREHOUSE SCHOOL OF MEDICINE · PI SULLIVAN, LOUIS W. · 2002 to 2002
$1.3M
Discovering novel biomarkers predictive of Tubal infertility caused by ChlamydiaSC2HD086066 · NICHD · MOREHOUSE SCHOOL OF MEDICINE · PI OMOSUN, YUSUF OSEOBHUNU · 2015 to 2017
$425k
NCRR NIH HHS C06 RR018386NIAID NIH HHS R01 AI041231NIAID NIH HHS R01 AI126897NICHD NIH HHS SC2 HD086066
6 · The paper itself

Abstract

We tested the hypothesis that the impact of the Fms-like tyrosine kinase 3-ligand (Flt3L; FL) on recombinant

Indexed as

Bacterial VaccinesImmunity, MucosalAnimalsAntibodies, BacterialBacterial ProteinsChlamydia trachomatisFemalefms-Like Tyrosine Kinase 3Immunoglobulin ALymphogranuloma VenereumMicePorinsTh1 CellsTh2 CellsVibrio choleraeAntibodies, BacterialBacterial ProteinsBacterial VaccinesFlt3 protein, mousefms-Like Tyrosine Kinase 3Immunoglobulin APorB protein, Chlamydia trachomatisPorinsChlamydia trachomatisC. muridarumFlt3LPmpDPorBprotective immunityvaccine delivery route

Identifiers

PMID31333682
PMCPMC6621642
OpenAlexW2954145925

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.