ArticleWorld journal of gastroenterology2019
Gut microbiota contributes to the distinction between two traditional Chinese medicine syndromes of ulcerative colitis.
Article in World journal of gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- The application of Tong-fu therapeutic method on ulcerative colitis: A systematic review and meta-analysis for efficacy and safety of rhubarb-based therapy.Frontiers in pharmacology · 2022Pooled it
- Phylosymbiosis and Parallel Geographical Patterns in the Gut Microbiota of Desert-Dwelling Amphibians and Reptiles.Integrative zoology · 2026Article
- The mechanism of indigo naturalis and its active ingredients against ulcerative colitis.Scientific reports · 2026Article
- A comparative study on the clinical differences in traditional Chinese medicine pattern in ulcerative colitis utilizing multidimensional data.Frontiers in medicine · 2026Article
- Difference of the gut microbiota of premature ovarian insufficiency in two traditional Chinese syndromes.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2025Article
- Targeting CD4+ T cells through gut microbiota: therapeutic potential of traditional Chinese medicine in inflammatory bowel disease.Frontiers in cellular and infection microbiology · 2025Review
- The gut microbiome is associated with susceptibility to febrile malaria in Malian children.Nature communications · 2024Article
- Two-Year Study on the Intra-Individual Dynamics of Gut Microbiota and Short-Chain Fatty Acids Profiles in Healthy Adults.Microorganisms · 2024Article
- Susceptibility to febrile malaria is associated with an inflammatory gut microbiome.Research square · 2024Article
- Gut bacteriome in inflammatory bowel disease: An update on recent advances.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024Review
- Traditional Chinese herbal formulas modulate gut microbiome and improve insomnia in patients with distinct syndrome types: insights from an interventional clinical study.Frontiers in cellular and infection microbiology · 2024Article
- TCM syndrome differentiation in colorectal cancer patients assisted by differences in gut microbiota: An exploratory study.Heliyon · 2023Article
- Article
- Role of adherent invasiveWorld journal of clinical cases · 2022Review
- Fecal microbiota transplantation in the metabolic diseases: Current status and perspectives.World journal of gastroenterology · 2022Review
- Intestinal Microecology of Mice Exposed to TiOFoods (Basel, Switzerland) · 2022Article
- Network Pharmacology Integrated Molecular Docking Revealed the Mechanism of Jianpi Yiqi Taohua Decoction Against Ulcerative Colitis.Medical science monitor : international medical journal of experimental and clinical research · 2022Article
- Traditional Chinese Medicine Alleviates Ulcerative Colitis via Modulating Gut Microbiota.Evidence-based complementary and alternative medicine : eCAM · 2022Review
- Efficacy and Safety of Probiotics Combined With Traditional Chinese Medicine for Ulcerative Colitis: A Systematic Review and Meta-Analysis.Frontiers in pharmacology · 2022Review
- Standards for Collection, Preservation, and Transportation of Fecal Samples in TCM Clinical Trials.Frontiers in cellular and infection microbiology · 2022Article
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUlcerative colitis (UC) is considered to be closely associated with alteration of intestinal microorganisms. According to the traditional Chinese medicine (TCM) theory, UC can be divided into two disease syndromes called Pi-Xu-Shi-Yun (PXSY) and Da-Chang-Shi-Re (DCSR). The relationships among gut microbiota, TCM syndromes, and UC pathogenesis have not been well investigated.
aimTo investigate the role of gut microbiota in UC and the distinction of microbiota dysbiosis between PXSY and DCSR syndromes.
methodsFrom May 2015 to February 2016, UC patients presenting to LongHua Hospital who met the established inclusion and exclusion criteria were enrolled in this retrospective study. Fresh stool specimens of UC patients with PXSY or DCSR were collected. The feces of the control group came from the health examination population of Longhua Hospital. The composition of gut bacterial communities in stool samples was determined by the pyrosequencing of 16S ribosomal RNA. The high-throughput sequencing reads were processed with QIIME, and biological functions were predicted using Phylogenetic Investigation of Communities by Reconstruction of Unobserved States.
resultsThe composition of gut bacterial communities in 93 stool samples (30 healthy controls, 32 patients with PXSY syndrome, and 31 patients with DCSR syndrome) was determined by the pyrosequencing of 16S ribosomal RNA. Beta diversity showed that the composition of the microbiota was different among the three groups. At the family level, Porphyromonadaceae, Rikeneliaceae, and Lachnospiraceae significantly decreased while Enterococcus, Streptococcus, and other potential pathogens significantly increased in UC patients compared to healthy subjects. At the genus level,
conclusionOur study suggests that the gut microbiota contributes to the distinction between the two TCM syndromes of UC.
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