ReviewWorld journal of gastroenterology2019
Revisiting the liver's role in transplant alloimmunity.
Review in World journal of gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed.
- Selective decrease of donor-reactive TScience translational medicine · 2022Trial
- Article
- The United States Experience With Combined Lung+Liver Transplantation.Annals of thoracic surgery short reports · 2026Article
- Postoperative Outcomes and Risk Profiles in Dual Liver-Lung Transplantation: A Single-Center Retrospective Analysis.Journal of transplantation · 2026Article
- Update on the Complications and Management of Liver Cirrhosis.Medical sciences (Basel, Switzerland) · 2025Review
- Advanced omics approaches in liver transplant settings: current applications and future prospectives.Frontiers in immunology · 2025Review
- Immunocompatibility in transplantation: adapting to a changing therapeutic landscape.Frontiers in immunology · 2025Review
- Combined Organ Transplantation in Patients with Advanced Liver Disease.Seminars in liver disease · 2024Review
- Subsequent kidney transplant after pediatric heart transplant: Prevalence and risk factors.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2024Article
- Relative carcinogenicity of tacrolimusWorld journal of hepatology · 2024Article
- Review of pediatric combined heart-liver transplantation: A roadmap to success.Pediatric transplantation · 2023Review
- Role of the immune system in liver transplantation and its implications for therapeutic interventions.MedComm · 2023Review
- Progress in Combined Liver-lung Transplantation at a Single Center.Transplantation direct · 2023Article
- Use of immune checkpoint inhibitors in solid organ transplant recipients with advanced cutaneous malignancies.Frontiers in transplantation · 2023Article
- Immunology of simultaneous liver and kidney transplants with identification and prevention of rejection.Frontiers in transplantation · 2022Review
- Liver mesenchymal stem cells are superior inhibitors of NK cell functions through differences in their secretome compared to other mesenchymal stem cells.Frontiers in immunology · 2022Article
- Cell-Mediated Therapies to Facilitate Operational Tolerance in Liver Transplantation.International journal of molecular sciences · 2021Review
- ComparableFrontiers in cell and developmental biology · 2021Article
- Self-Centered Function of Adaptive Immunity in Regulation of Immune Responses and in Tolerance.Journal of immunology research · 2021Review
- Differences in Liver Graft Survival by Recipient Sex.Transplantation direct · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The transplanted liver can modulate the recipient immune system to induce tolerance after transplantation. This phenomenon was observed nearly five decades ago. Subsequently, the liver's role in multivisceral transplantation was recognized, as it has a protective role in preventing rejection of simultaneously transplanted solid organs such as kidney and heart. The liver has a unique architecture and is home to many cells involved in immunity and inflammation. After transplantation, these cells migrate from the liver into the recipient. Early studies identified chimerism as an important mechanism by which the liver modulates the human immune system. Recent studies on human T-cell subtypes, cytokine expression, and gene expression in the allograft have expanded our knowledge on the potential mechanisms underlying immunomodulation. In this article, we discuss the privileged state of liver transplantation compared to other solid organ transplantation, the liver allograft's role in multivisceral transplantation, various cells in the liver involved in immune responses, and the potential mechanisms underlying immunomodulation of host alloresponses.
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Registered trials
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