Evidence map›Paper›PMID 31333198›Full record

SynthesisJournal of medical Internet research2019

Digital Mental Health Interventions for Depression, Anxiety, and Enhancement of Psychological Well-Being Among College Students: Systematic Review.

Emily G Lattie, Elizabeth C Adkins, Nathan Winquist, Colleen Stiles-Shields, Q Eileen Wafford, Andrea K Graham

5 registry-linked trialsOpen access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Journal of medical Internet research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 383 papers, 21 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
383citing papers in PubMed, 21 pooled it
43.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05083676 nacompletednot on this mapstarted 2022, after this paper: background citation

A Study Protocol on Peer Digital Acceset (PDA): A Randomized Controlled Trial to Translate Online Peer Support for Youth Mental Well-being

TypeinterventionalSponsorThe N.1 Institute for Health (N.1)Ran2022 to 2023Enrolled100ConditionsMental Health IssueArmsAcceset Intervention
NCT05234970 nacompletednot on this mapstarted 2022, after this paper: background citation

iWellness Study: Evaluation of a CBT Chatbot App to Promote Mental Wellness in Students

TypeinterventionalSponsorHarvard UniversityRan2022 to 2022Enrolled289ConditionsDepression, AnxietyArmsWysa, Harvard College App
NCT06773468 nacompletednot on this mapstarted 2023, after this paper: background citation

Evaluating Knowledge Mobilization for Stress Management in University Students

TypeinterventionalSponsorMcGill UniversityRan2023 to 2024Enrolled313ConditionsStress, Coping, Digital Intervention, University StudentsArmsstress management
NCT07086001 nacompletednot on this mapstarted 2022, after this paper: background citation

Does it Work? Examining the Acceptability and Effectiveness of a Self-Directed, Web-Based Resource for Stress and Coping in University: Randomized Controlled Trial

TypeinterventionalSponsorMcGill UniversityRan2022 to 2022Enrolled242ConditionsStress, Coping, Coping Behavior, Well-Being (Psychological Flourishing)Armsstress management and coping
NCT07242378 nacompletednot on this mapstarted 2023, after this paper: background citation

Evaluating Knowledge Mobilization Sustainability Approaches for Stress Management in University Students

TypeinterventionalSponsorMcGill UniversityRan2023 to 2024Enrolled331ConditionsStress, Coping, Well-being, MindfulnessArmsSustainability of stress management strategy use, Stress management
3 · Its place in the literature

Who cites it

383 citing papers in PubMed, 21 syntheses or guidelines pooled it, 796 citations in OpenAlex.

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  7. Enhancing Postsecondary Students' Dietary Behaviours: A Systematic Review of Mobile Health Interventions.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025
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323 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Emily G LattieCenter for Behavioral Intervention Technologies, Northwestern University, Chicago, IL, United States.ORCID 0000-0002-3069-5996
Elizabeth C AdkinsCenter for Behavioral Intervention Technologies, Northwestern University, Chicago, IL, United States.ORCID 0000-0002-0651-3013
Nathan WinquistCenter for Behavioral Intervention Technologies, Northwestern University, Chicago, IL, United States.ORCID 0000-0001-8932-4746
Colleen Stiles-ShieldsDepartment of Psychiatry and Behavioral Sciences, Rush University Medical Center, Chicago, IL, United States.ORCID 0000-0002-6759-8380
Q Eileen WaffordGalter Health Sciences Library and Learning Center, Northwestern University, Chicago, IL, United States.ORCID 0000-0001-5228-8219
Andrea K GrahamCenter for Behavioral Intervention Technologies, Northwestern University, Chicago, IL, United States.ORCID 0000-0002-9736-8906
Northwestern University · USRush University Medical Center · US

Funding

Testing Intervention Strategies for Addressing Obesity and Binge EatingK01DK116925 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GRAHAM, ANDREA KASS · 2018 to 2022
$799k
Expanding College Student Mental Health with Stress Management Mobile TechnologiesK08MH112878 · NIMH · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LATTIE, EMILY GARDINER · 2017 to 2021
$746k
NIDDK NIH HHS K01 DK116925NIMH NIH HHS K08 MH112878
6 · The paper itself

Abstract

backgroundCollege students are increasingly reporting common mental health problems, such as depression and anxiety, and they frequently encounter barriers to seeking traditional mental health treatments. Digital mental health interventions, such as those delivered via the Web and apps, offer the potential to improve access to mental health treatment.

objectiveThis study aimed to review the literature on digital mental health interventions focused on depression, anxiety, and enhancement of psychological well-being among samples of college students to identify the effectiveness, usability, acceptability, uptake, and adoption of such programs.

methodsWe conducted a systematic review using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines (registration number CRD42018092800), and the search strategy was conducted by a medical research librarian in the following databases: MEDLINE (Ovid), EMBASE (Elsevier), PsycINFO (EbscoHost), the Cochrane Library (Wiley), and Web of Science (Thomson Reuters) from the date of inception to April 2019. Data were synthesized using a systematic narrative synthesis framework, and formal quality assessments were conducted to address the risk of bias.

resultsA total of 89 studies met the inclusion criteria. The majority of interventions (71/89, 80%) were delivered via a website, and the most common intervention was internet-based cognitive behavioral therapy (28, 31%). Many programs (33, 37%) featured human support in the form of coaching. The majority of programs were either effective (42, 47%) or partially effective (30, 34%) in producing beneficial changes in the main psychological outcome variables. Approximately half of the studies (45, 51%) did not present any usability or acceptability outcomes, and few studies (4, 4%) examined a broad implementation of digital mental health interventions on college campuses. Quality assessments revealed a moderate-to-severe risk of bias in many of the studies.

conclusionsResults suggest that digital mental health interventions can be effective for improving depression, anxiety, and psychological well-being among college students, but more rigorous studies are needed to ascertain the effective elements of these interventions. Continued research on improving the user experience of, and thus user engagement with, these programs appears vital for the sustainable implementation of digital mental health interventions on college campuses.

Indexed as

AdultAnxietyDepressionHumansMental HealthPsychotherapyStudentsTelemedicineUniversitiesYoung AdulteHealthmental healthmHealthstudentsuniversities

Identifiers

PMID31333198
PMCPMC6681642
OpenAlexW2950229699

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.