Evidence map›Paper›PMID 31333055›Full record

ArticleJournal of the American Heart Association2019

Age-Related Trends in Home Blood Pressure, Home Pulse Rate, and Day-to-Day Blood Pressure and Pulse Rate Variability Based on Longitudinal Cohort Data: The Ohasama Study.

Michihiro Satoh, Hirohito Metoki, Kei Asayama, Takahisa Murakami, Ryusuke Inoue, Megumi Tsubota-Utsugi, Ayako Matsuda, Takuo Hirose, Azusa Hara, Taku Obara and 5 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Seasonal variation in day-to-day blood pressure variability: large-scale within-individual home blood pressure data.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
  4. Article
  5. Article
  6. Article
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  8. Detailed cross-sectional association between traditional risk factors and high systolic blood pressure in a Japanese population.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  9. The importance of regular home blood pressure monitoring over the life course.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  10. Relationship between defecation status and blood pressure level or blood pressure variability.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  11. Long-term changes in blood pressure and their health impact.Hypertension research : official journal of the Japanese Society of Hypertension · 2023
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Age-related changes in the risk of high blood pressure.Frontiers in cardiovascular medicine · 2022
    Article
  17. Article
  18. Observational
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 1 country.

Michihiro SatohDivision of Public Health, Hygiene and Epidemiology Faculty of Medicine Tohoku Medical and Pharmaceutical University Sendai Japan.
Hirohito MetokiDivision of Public Health, Hygiene and Epidemiology Faculty of Medicine Tohoku Medical and Pharmaceutical University Sendai Japan.
Kei AsayamaTohoku Institute for Management of Blood Pressure Sendai Japan.
Takahisa MurakamiDivision of Public Health, Hygiene and Epidemiology Faculty of Medicine Tohoku Medical and Pharmaceutical University Sendai Japan.
Ryusuke InoueDepartment of Medical Information Technology Center Tohoku University Hospital Sendai Japan.
Megumi Tsubota-UtsugiDepartment of Hygiene and Preventive Medicine Iwate Medical University School of Medicine Iwate Japan.
Ayako MatsudaDepartment of Hygiene and Public Health Teikyo University School of Medicine Tokyo Japan.
Takuo HiroseDivision of Nephrology and Endocrinology Faculty of Medicine Tohoku Medical and Pharmaceutical University Sendai Japan.
Azusa HaraDivision of Drug Development and Regulatory Science Faculty of Pharmacy Keio University Tokyo Japan.
Taku ObaraDepartment of Preventive Medicine and Epidemiology Tohoku Medical Megabank Organization Tohoku University Sendai Japan.
Masahiro KikuyaDepartment of Preventive Medicine and Epidemiology Tohoku Medical Megabank Organization Tohoku University Sendai Japan.
Kyoko NomuraDepartment of Public Health Akita University Graduate School of Medicine Akita Japan.
Atsushi HozawaDepartment of Preventive Medicine and Epidemiology Tohoku Medical Megabank Organization Tohoku University Sendai Japan.
Yutaka ImaiTohoku Institute for Management of Blood Pressure Sendai Japan.
Takayoshi OhkuboTohoku Institute for Management of Blood Pressure Sendai Japan.
Teikyo University · JPTohoku Medical and Pharmaceutical University · JPTohoku University · JPTohoku University Hospital · JPAkita University · JPIwate Medical University · JPKeio University · JPTohoku Medical Megabank Organization · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Home blood pressure is a more accurate prognosticator than office blood pressure and allows the observation of day-to-day blood pressure variability. Information on blood pressure change during the life course links the prediction of blood pressure elevation with age. We prospectively assessed age-related trends in home blood pressure, home pulse rate, and their day-to-day variability evaluated as a coefficient of variation. Methods and Results We examined 1665 participants (men, 36.0%; mean age, 56.2 years) from the general population of Ohasama, Japan. A repeated-measures mixed linear model was used to estimate the age-related trends. In a mean of 15.9 years, we observed 5438 points of measurements including those at baseline. The home systolic blood pressure linearly increased with age and was higher in men than in women aged <70 years. There was an inverse-U-shaped age-related trend in home diastolic blood pressure. The day-to-day home systolic blood pressure linearly increased with age in individuals aged >40 years. However, an U-shaped age-related trend in day-to-day diastolic blood pressure variability with the nadir point at 65 to 69 years of age was observed. No significant sex differences in the day-to-day blood pressure variability were observed (P≥0.22). The average and day-to-day variability of home pulse rate decreased with age but were lower and higher, respectively, in men than in women. Conclusions The current descriptive data are needed to predict future home blood pressure and pulse rate. The data also provide information on the mechanism of day-to-day blood pressure and pulse rate variability.

Indexed as

Heart RateAgedAge FactorsBlood Pressure DeterminationCohort StudiesFemaleHumansLongitudinal StudiesMaleMiddle AgedProspective Studiesblood pressureblood pressure measurement/monitoringepidemiologyheart rate/heart rate variabilityhome blood pressure

Identifiers

PMID31333055
PMCPMC6761623
OpenAlexW2964247692

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.