Evidence map›Paper›PMID 31332982›Full record

ArticleAllergy, asthma & immunology research2019

Clinical Features and Culprit Food Allergens of Korean Adult Food Allergy Patients: A Cross-Sectional Single-Institute Study.

Sang Chul Lee, Sung Ryeol Kim, Kyung Hee Park, Jae Hyun Lee, Jung Won Park

Open access · hybridAbstract read
In one paragraph

Article in Allergy, asthma & immunology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Buckwheat Allergy in Asia.Current allergy and asthma reports · 2024
    Review
  6. Neglected but Clinically Relevant Allergens in Korea.Current allergy and asthma reports · 2024
    Review
  7. Review
  8. Article
  9. Article
  10. Food allergy in Sri Lanka - A comparative study.The World Allergy Organization journal · 2022
    Article
  11. Article
  12. Recent update on the management of anaphylaxis.Clinical and experimental emergency medicine · 2021
    Article
  13. Allergenicity and Stability of 6 New Korean Bony Fish Extracts.Allergy, asthma & immunology research · 2021
    Article
  14. Review
  15. Article
  16. Allergens of Regional Importance in Korea.Frontiers in allergy · 2021
    Review
  17. Food Allergy from Infancy Through Adulthood.The journal of allergy and clinical immunology. In practice · 2020
    Review
  18. Article
  19. Revised Pollen Calendar in Korea.Allergy, asthma & immunology research · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sang Chul LeeDivision of Allergy and Immunology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-5318-6804
Sung Ryeol KimDivision of Allergy and Immunology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-7418-0049
Kyung Hee ParkDivision of Allergy and Immunology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-3605-5364
Jae Hyun LeeDivision of Allergy and Immunology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-0760-0071
Jung Won ParkDivision of Allergy and Immunology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-0249-8749
Yonsei University · KR

Funding

Ministry of Health and Welfare HI14C1324
6 · The paper itself

Abstract

purposeTo investigate the causative allergens and clinical characteristics of Korean adult patients with food allergy (FA).

methodsThis retrospective, cross-sectional single-institutional study enrolled Korean adult patients (n = 812) suspected of having FA. For diagnosis, causality assessment history taking, ImmunoCAP specific immunoglobulin E measurement and/or skin prick test were performed.

resultsAmong 812 patients, 415 were diagnosed as having FA. The most common causative allergen was fruit, with a diagnosis of pollen food allergy syndrome (PFAS: 155, 37.3%), followed by crustaceans (111, 26.7%), wheat (63, 15.1%), fruits in patients without PFAS(43, 10.3%), buckwheat (31, 7.4%), peanut (31, 7.4%), walnut (25, 6.0%), red meat due to reaction to galactose-α-1,3-galactose (α-Gal) (8, 1.9%), and silkworm pupa (13, 3.1%). Allergy to egg, milk, fish, or shellfish was rare in Korean adults. One-third of patients with FA exhibited multiple FAs (238/415, 57.3%); the average number of causative allergens was 2.39. About 129 patients (31.0%) were diagnosed as having anaphylaxis; in these patients, wheat was the most frequent causative food. Twenty patients were further diagnosed with food-dependent exercise-induced anaphylaxis (FDEIA); all were due to wheat. In particular, crustaceans, wheat, PFAS, buckwheat, and red meat (α-Gal) were also frequent causes of anaphylaxis.

conclusionsWheat, fruits with or without PFAS, and crustaceans are important and frequent causative allergens in Korean adult FA; these allergens differ from those found in childhood FA. It is notable that non-classic allergies, such as PFAS, FDEIA, and α-Gal allergy, are the important causes of anaphylaxis in Korean adult FA.

Indexed as

Adultsanaphylaxisfood allergenfood allergyKorea

Identifiers

PMID31332982
PMCPMC6658406
OpenAlexW2963310708

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.