Evidence map›Paper›PMID 31332974›Full record

ArticleAllergy, asthma & immunology research2019

Cough-Related Laryngeal Sensations and Triggers in Adults With Chronic Cough: Symptom Profile and Impact.

Ha Kyeong Won, Sung Yoon Kang, Yewon Kang, Jin An, Ji Hyang Lee, Sang Min Lee, Jae Woo Kwon, Min Hye Kim, Eun Jung Jo, Seung Eun Lee and 8 more

Open access · hybridAbstract read
In one paragraph

Article in Allergy, asthma & immunology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 10 institutions in 2 countries.

Ha Kyeong Won *Department of Allergy and Clinical Immunology, Airway Sensation and Cough Research Laboratory, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-8127-7885
Sung Yoon Kang *Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Korea.ORCID https://orcid.org/0000-0001-5505-3028
Yewon KangDepartment of Internal Medicine, Pusan National University School of Medicine, Pusan National University Hospital, Busan, Korea.ORCID https://orcid.org/0000-0002-7068-313X
Jin AnDepartment of Allergy and Clinical Immunology, Airway Sensation and Cough Research Laboratory, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-5416-2660
Ji Hyang LeeDepartment of Allergy and Clinical Immunology, Airway Sensation and Cough Research Laboratory, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-4286-3114
Sang Min LeeDepartment of Internal Medicine, Gachon University Gil Medical Center, Incheon, Korea.ORCID https://orcid.org/0000-0002-9568-2096
Jae Woo KwonDepartment of Internal Medicine, Kangwon National University School of Medicine, Chuncheon, Korea.ORCID https://orcid.org/0000-0003-1639-3606
Min Hye KimDepartment of Internal Medicine, College of Medicine, Ewha Womans University, Seoul, Korea.ORCID https://orcid.org/0000-0002-1775-3733
Eun Jung JoDepartment of Internal Medicine, Pusan National University School of Medicine, Pusan National University Hospital, Busan, Korea.ORCID https://orcid.org/0000-0003-3712-6216
Seung Eun LeeDepartment of Internal Medicine, Pusan National University Yangsan Hospital, Yangsan, Korea.ORCID https://orcid.org/0000-0002-4266-7722
Sae Hoon KimDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID https://orcid.org/0000-0002-2572-5302
Sang Heon KimDepartment of Internal Medicine, Hanyang University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0001-8398-4444
Yoon Seok ChangDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID https://orcid.org/0000-0003-3157-0447
Sang Hoon KimDepartment of Internal Medicine, Eulji Hospital, Eulji University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-4105-0552
Byung Jae LeeDivision of Allergy, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-6940-0836
Sang Heon ChoDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-7644-6469
Surinder S BirringCentre for Human & Applied Physiological Sciences, School of Basic & Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, London, UK.
Woo Jung SongDepartment of Allergy and Clinical Immunology, Airway Sensation and Cough Research Laboratory, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. swj0126@amc.seoul.kr.ORCID https://orcid.org/0000-0002-4630-9922
Ulsan College · KREulji University · KRGachon University Gil Medical Center · KRPusan National University Hospital · KREwha Womans University · KRKangwon National University · KRKing's College London · GBSamsung Medical Center · KRSeoul National University · KRSeoul National University Bundang Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRecent evidence suggests that cough hypersensitivity may be a common feature of chronic cough in adults. However, the clinical relevance remains unclear. This study evaluated the cough-related symptom profile and the clinical relevance and impact of cough hypersensitivity in adults with chronic cough.

methodsThis cross-sectional multi-center study compared cough-related laryngeal sensations and cough triggers in patients with unexplained chronic cough following investigations and in unselected patients newly referred for chronic cough. A structured questionnaire was used to assess abnormal laryngeal sensations and cough triggers. Patients with unexplained cough were also evaluated using the Leicester Cough Questionnaire (LCQ) and a cough visual analogue scale (VAS), and these scores were assessed for correlations with the number of triggers and laryngeal sensations.

resultsThis study recruited 478 patients, including 62 with unexplained chronic cough and 416 with chronic cough. Most participants reported abnormal laryngeal sensations and cough triggers. Laryngeal sensations (4.4 ± 1.5 vs. 3.9 ± 1.9;

conclusionsCough hypersensitivity may be a common feature in adult patients with chronic cough, especially those with unexplained chronic cough. Cough-related health status and cough severity were inversely associated with the number of triggers and laryngeal sensations, suggesting potential relevance of assessing cough hypersensitivity in chronic cough patients.

Indexed as

Coughhypersensitivitysymptom assessment

Identifiers

PMID31332974
PMCPMC6658400
OpenAlexW2962685666

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.