Evidence map›Paper›PMID 31332687›Full record

ArticleThe protein journal2019

Recombinant Expression and Bioactivity Characterization of TAT-Fused Thymosin β10.

Kunzhi Jia, Ming Lin, Defeng Kong, Qi Jia

Abstract read
PubMed Publisher
In one paragraph

Article in The protein journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kunzhi JiaThe Ministry of Education Key Laboratory of Biopesticide and Chemical Biology, School of Life Science, Fujian Agriculture and Forestry University, Fuzhou, China.
Ming LinThe Ministry of Education Key Laboratory of Biopesticide and Chemical Biology, School of Life Science, Fujian Agriculture and Forestry University, Fuzhou, China.
Defeng KongKey Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops, Ministry of Education/College of Crop Science, Fujian Agriculture and Forestry University, Jinshan, Fuzhou, 350002, China.
Qi JiaKey Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops, Ministry of Education/College of Crop Science, Fujian Agriculture and Forestry University, Jinshan, Fuzhou, 350002, China. jiaqi@fafu.edu.cn.
Fujian Agriculture and Forestry University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thymosin beta 10 (TB10) is one of the common members among beta-thymosins. Human TB10 is reported to play a role in anti-angiogenesis and inhibition of cell migration during the tumorigenesis or metastasis of some certain cancers. Thus, it would be a potent clinical agent. In the present study, the coding sequence of TB10 was optimized based on the codon preference of Escherichia coli and cloned to pET28a (+) by chemical synthesis and molecular cloning methods. The recombinant protein was highly expressed employing E. coli expressing system and purified by a simple step of Ni

Indexed as

Recombinant Fusion ProteinsThymosinAngiogenesis InhibitorsCloning, MolecularEscherichia coliAngiogenesis InhibitorsRecombinant Fusion ProteinsThymosinthymosin beta(10)Anti-angiogenesisCell migrationPurificationTATThymosin β10

Identifiers

PMID31332687
OpenAlexW2964271571

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.