Evidence map›Paper›PMID 31332649›Full record

Trial reportClinical drug investigation2019

Bronchodilator Efficacy of a Single-Dose 12/400-µg Formoterol/Budesonide Combination as a Dry Powder for Inhalation Delivered by Discair

Pinar Yildiz, Mesut Bayraktaroglu, Didem Gorgun, Kivanc Yuksel

Registry-linked trialAbstract readClinical Trial, Phase IV
PubMed Publisher
In one paragraph

Trial report in Clinical drug investigation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03028701 (Assessment of Bronchodilator Efficacy of Formoterol/Budesonide 12/400 mcg Via Discair in Chronic Obstructive Pulmonary Disease), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03028701 phase4completednot on this map

Assessment of Bronchodilator Efficacy of Formoterol/Budesonide 12/400 mcg Via Discair in Chronic Obstructive Pulmonary Disease (COPD)

TypeinterventionalSponsorNeutec Ar-Ge San ve Tic A.ŞRan2015 to 2017Enrolled33ConditionsCopdArmsFormoterol/Budesonide 12/400 mcg Discair
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pinar YildizUniversity of Health Sciences, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, Istanbul, Turkey. pinary70@yahoo.com.ORCID http://orcid.org/0000-0002-6650-1495
Mesut BayraktarogluUniversity of Health Sciences, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-9063-1118
Didem GorgunUniversity of Health Sciences, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-7067-9360
Kivanc YukselCenter for Drug Research and Development and Pharmacokinetic Applications (ARGEFAR), Ege University, Izmir, Turkey.ORCID http://orcid.org/0000-0003-3491-0099

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesA patient-friendly and easy-to-use multi-dose dry powder inhaler, Discair

methodsA total of 33 male patients with moderate-to-severe, chronic obstructive pulmonary disease were included in this single-arm, open-label, phase IV trial. The primary efficacy parameters were the average maximum change in forced expiratory volume in 1 s (FEV

resultsThe mean post-bronchodilator FEV

conclusionsOur findings revealed significant changes from baseline in post-bronchodilator peak and average FEV

trial registrationClinicalTrials.gov Identifier NCT03028701.

Indexed as

Administration, InhalationAgedBronchodilator AgentsBudesonideDrug Delivery SystemsDry Powder InhalersForced Expiratory VolumeFormoterol FumarateHumansMaleMetered Dose InhalersMiddle AgedPulmonary Disease, Chronic ObstructiveRespiratory Function TestsSeverity of Illness IndexTreatment OutcomeBronchodilator AgentsBudesonideFormoterol Fumarate

Identifiers

PMID31332649

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.