ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2020
Identifying risk factors for depression and anxiety symptoms in patients with chronic lymphocytic leukemia.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Examining anxiety and depression in haematology cancer patients in ongoing treatment and under watchful waiting: A systematic review and meta-analysis.European journal of cancer care · 2022Pooled it
- Bidirectional relationship between anxiety disorder and cancer: a longitudinal population-based cohort study.BMC cancer · 2025Article
- Prognostic impacts of marital status and other socioeconomic factors in patients with chronic lymphocytic leukemia: an analysis of SEER database.Therapeutic advances in hematology · 2025Article
- Effects of a strength physical exercise program in chronic lymphocytic leukemia patients on quality of life, mental health, and frailty: a randomized controlled trial study protocol.Frontiers in sports and active living · 2025Article
- Impact of comorbid subthreshold depressive symptoms on cancer-related fatigue and complications in adults with leukemia.World journal of psychiatry · 2024Article
- Depression and anxiety in cancer patient enrolled in clinical trials with serious adverse events.Cancer medicine · 2023Article
- Depression and anxiety among hemophilia patients enrolled in clinical trials: a multi-center cohort study.Annals of hematology · 2023Article
- Empathetic nursing with mindful cognitive therapy for fatigue, depression, and negative emotions in leukemia patients undergoing long-term chemotherapy.World journal of clinical cases · 2022Article
- Precancer and cancer-associated depression and anxiety among older adults with blood cancers in the United States.Blood advances · 2022Article
- Factors associated with and risk factors for depression in cancer patients - A systematic literature review.Translational oncology · 2022Review
- Short Sleep Duration as a Risk Factor for Depression, Anxiety and Fatigue in Patients with Leukemia.Neuropsychiatric disease and treatment · 2022Article
- Predicting anxiety in cancer survivors presenting to primary care - A machine learning approach accounting for physical comorbidity.Cancer medicine · 2021Article
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Authors and funding
6 authors.
Funding
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Abstract
purposeThis study assessed whether empirically supported risk factors can identify future depression and anxiety symptoms in a specific cancer type, chronic lymphocytic leukemia (CLL).
methodsPatients enrolled in a CLL treatment clinical trial (N = 106) participated at baseline following informed consent and prior to treatment initiation. Risk factors with empirical support (personal or family psychiatric history, recurrent, advanced or progressive disease, low socioeconomic status, gender, medical comorbidities, and single marital status) and additional risk factors (cancer-specific stress, social contacts, negative life events, absolute lymphocyte counts, treatment group, and fatigue) were measured at baseline to predict depression and anxiety symptoms at 12 months.
resultsData show 14% (n = 15) and 12% (n = 13) of patients experienced moderate-severe depression and anxiety symptoms, respectively. Multiple linear regression analyses found medical comorbidities predicted 12-month anxiety symptoms (p < 0.05). Also, negative life events predicted depression and anxiety symptoms and fatigue predicted depression symptoms (p < 0.05).
conclusionEmpirically supported risk factors associated with depression and anxiety symptoms are limited in predicting future depression and anxiety symptoms beyond initial screening in patients with CLL. In addition to levels of depression and anxiety symptoms at baseline, negative life events, higher levels of fatigue, and greater medical comorbidities were associated with future depression or anxiety symptoms in patients with CLL.
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