Evidence map›Paper›PMID 31332478›Full record

ArticleNeuroradiology2019

Intra-arterial chemotherapy for retinoblastoma: the dosimetric impact.

Andrea Guasti, Sara Leonini, Eugenio Bertelli, Roberta Baldi, Paola Gennari, Samuele Cioni, Ignazio Maria Vallone, Daniele Giuseppe Romano, Tommaso Casseri, Leonardo Guerrini and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in Neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Andrea GuastiDepartment of Medical Physics, Azienda USL Toscana sud est, Siena, Italy.
Sara LeoniniUnit of Neuroimaging and Neurointervention, Azienda Ospedaliera Universitaria Senese, Siena, Italy. s_leonini@yahoo.it.ORCID http://orcid.org/0000-0001-7158-4427
Eugenio BertelliDepartment of Molecular and Developmental Medicine, University of Siena, Siena, Italy.
Roberta BaldiDepartment of Diagnostic Imaging, Azienda Ospedaliera Universitaria Senese, Siena, Italy.
Paola GennariUnit of Neuroimaging and Neurointervention, Azienda Ospedaliera Universitaria Senese, Siena, Italy.
Samuele CioniUnit of Neuroimaging and Neurointervention, Azienda Ospedaliera Universitaria Senese, Siena, Italy.
Ignazio Maria ValloneUnit of Neuroimaging and Neurointervention, Azienda Ospedaliera Universitaria Senese, Siena, Italy.
Daniele Giuseppe RomanoUnit of Neuroimaging and Neurointervention, Azienda Ospedaliera Universitaria Senese, Siena, Italy.
Tommaso CasseriDepartment of Medical, Surgical and Neuro Sciences, Diagnostic Imaging, University of Siena, Siena, Italy.
Leonardo GuerriniDepartment of Medical Physics, Azienda Ospedaliera Universitaria Senese, Siena, Italy.
Annunziata Elena La RoccaDepartment of Medical Physics, Azienda Ospedaliera Universitaria Senese, Siena, Italy.
Paolo Gambini Della ScalaUnit of Neuroimaging and Neurointervention, Azienda Ospedaliera Universitaria Senese, Siena, Italy.
Sonia De FrancescoDepartment of Medicine, Surgery and Neuroscience, Unit of Ophthalmology, Azienda Ospedaliera Universitaria Senese, Siena, Italy.
Theodora HadjistilianouDepartment of Medicine, Surgery and Neuroscience, Unit of Ophthalmology, Azienda Ospedaliera Universitaria Senese, Siena, Italy.
Sandra BraccoUnit of Neuroimaging and Neurointervention, Azienda Ospedaliera Universitaria Senese, Siena, Italy.
Azienda Ospedaliera Universitaria Senese · ITUniversity of Siena · ITAzienda Usl Toscana Centro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePurposes are (1) to measure main radiation parameters and (2) to propose a method to estimate the absorbed doses of internal organs starting from DAP values. Measuring the exposition of internal organs by repeated irradiations on an anthropomorphic phantom with the same settings used in vivo, we could establish correlations between (1) DAP and the dose recorded by a dosimeter placed along the X-ray beam entrance pathway; (2) the dose recorded by the same dosimeter and the absorbed dose in internal organs.

methodsForty-four consecutive patients (16 males, 28 females) (mean age 35.4 months) treated at our institution with IAC (216 procedures: 196 via the ICA and 20 into branches of the ECA) were included in this prospective study. IAC was divided into 5 phases. Fluoroscopic time, DAP, and ESD were measured.

resultsThe mean DAP was 595 ± 445 cGy cm

conclusionThis paper describes a method of absorbed dose estimation providing ranges used clinically in a single practice and the basis for further prospective studies.

Indexed as

FluoroscopyRadiation DosageAdolescentAngiographyAntineoplastic AgentsChildChild, PreschoolFemaleHumansInfantInfusions, Intra-ArterialMalePhantoms, ImagingProspective StudiesRadiometryRetinal NeoplasmsAntineoplastic AgentsAbsorbed doseDose expositionIntra-arterial chemotherapyRadiation parametersRetinoblastoma

Identifiers

PMID31332478
OpenAlexW2963900284

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.