Evidence map›Paper›PMID 31332261›Full record

ArticleScientific reports2019

Tracking the Growth of Superparamagnetic Nanoparticles with an In-Situ Magnetic Particle Spectrometer (INSPECT).

Ankit Malhotra, Anselm von Gladiss, André Behrends, Thomas Friedrich, Alexander Neumann, Thorsten M Buzug, Kerstin Lüdtke-Buzug

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ankit MalhotraInstitute of Medical Engineering, University of Lübeck, Ratzeburger Allee 160, Lübeck, Germany. malhotra@imt.uni-luebeck.de.
Anselm von GladissInstitute of Medical Engineering, University of Lübeck, Ratzeburger Allee 160, Lübeck, Germany.ORCID http://orcid.org/0000-0003-1340-4576
André BehrendsInstitute of Medical Engineering, University of Lübeck, Ratzeburger Allee 160, Lübeck, Germany.
Thomas FriedrichInstitute of Medical Engineering, University of Lübeck, Ratzeburger Allee 160, Lübeck, Germany.
Alexander NeumannInstitute of Medical Engineering, University of Lübeck, Ratzeburger Allee 160, Lübeck, Germany.
Thorsten M BuzugInstitute of Medical Engineering, University of Lübeck, Ratzeburger Allee 160, Lübeck, Germany.ORCID http://orcid.org/0000-0002-0399-8043
Kerstin Lüdtke-BuzugInstitute of Medical Engineering, University of Lübeck, Ratzeburger Allee 160, Lübeck, Germany. luedtke-buzug@imt.uni-luebeck.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetic Particle Spectroscopy (MPS) is a measurement technique to determine the magnetic properties of superparamagnetic iron oxide nanoparticles (SPIONs) in an oscillating magnetic field as applied in Magnetic Particle Imaging (MPI). State of the art MPS devices are solely capable of measuring the magnetization response of the SPIONs to an oscillatory magnetic excitation retrospectively, i.e. after the synthesis process. In this contribution, a novel in-situ magnetic particle spectrometer (INSPECT) is presented, which can be used to monitor the entire synthesis process from particle genesis via growth to the stable colloidal suspension of the nanoparticles in real time. The device is suitable for the use in a biochemistry environment. It has a chamber size of 72 mm such that a 100 ml reaction flask can be used for synthesis. For an alkaline-based precipitation, the change of magnetic properties of SPIONs during the nucleation and growth phase of the synthesis is demonstrated. The device is able to record the changes in the amplitude and phase spectra, and, in turn, the hysteresis. Hence, it is a powerful tool for an in-depth understanding of the nanoparticle formation dynamics during the synthesis process.

Identifiers

PMID31332261
PMCPMC6646392

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.