ArticleScientific reports2019
Asynchronous generation of oil droplets using a microfluidic flow focusing system.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 16 citations in OpenAlex.
- Periodic Flows in Microfluidics.Small (Weinheim an der Bergstrasse, Germany) · 2024Review
- Evaluation of Surface Treatments of PDMS Microfluidic Devices for Improving Small-Molecule Recovery with Application to Monitoring Metabolites Secreted from Islets of Langerhans.ACS measurement science au · 2023Article
- Quantitative study for control of air-liquid segmented flow in a 3D-printed chip using a vacuum-driven system.Scientific reports · 2022Article
- Rapid Prototyping of Organ-on-a-Chip Devices Using Maskless Photolithography.Micromachines · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Here, we show that long-term exposure of PDMS based microfluidic droplet generation systems to water can reverse their characteristics such that they generate oil-in-water droplets instead of water-in-oil droplets. The competition between two oil columns entering via the two side channels leads to asynchronous generation of oil droplets. We identify various modes of droplet generation, and study the size, gap and generation rate of droplets under different combinations of oil and water pressures. Oil droplets can also be generated using syringe pumps, various oil viscosities, and different combinations of immiscible liquids. We also demonstrate the ability to dynamically change the gap between the oil droplets from a few hundred microns to just a few microns in successive cycles using a latex balloon pressure pump. This method requires no special equipment or chemical treatments, and importantly can be reversed by long-term exposure of the PDMS surfaces to the ambient air.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.