ArticleScientific reports2019
An ICCD camera-based time-domain ultrasound-switchable fluorescence imaging system.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 16 citations in OpenAlex.
- Ultrasound-switchable fluorescence thermometry with dual detection channels using temperature-sensitive liposomes.Journal of biophotonics · 2024Article
- Improving the spatial resolution and signal-to-noise ratio of ultrasound switchable fluorescence imaging.Journal of biophotonics · 2024Article
- Monitoring Distribution of the Therapeutic Agent Dimethyl Sulfoxide via Solvatochromic Shift of Albumin-Bound Indocyanine Green.Sensors (Basel, Switzerland) · 2023Article
- Development of a preclinical CCD-based temperature modulated fluorescence tomography platform.Biomedical optics express · 2022Article
- Recent advances in ultrasound-controlled fluorescence technology for deep tissue optical imaging.Journal of pharmaceutical analysis · 2022Review
- Histogram clustering for rapid time-domain fluorescence lifetime image analysis.Biomedical optics express · 2021Article
- Ultrafast light field tomography for snapshot transient and non-line-of-sight imaging.Nature communications · 2021Article
- Near-infrared temperature-switchable fluorescence nanoparticles.Quantitative imaging in medicine and surgery · 2021Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fluorescence imaging in centimeter-deep tissues with high resolution is highly desirable for many biomedical applications. Recently, we have developed a new imaging modality, ultrasound-switchable fluorescence (USF) imaging, for achieving this goal. In our previous work, we successfully achieved USF imaging with several types of USF contrast agents and imaging systems. In this study, we introduced a new USF imaging system: an intensified charge-coupled device (ICCD) camera-based, time-domain USF imaging system. We demonstrated the principle of time-domain USF imaging by using two USF contrast agents. With a series of USF imaging experiments, we demonstrated the tradeoffs among different experimental parameters (i.e., data acquisition time, including CCD camera recording time and intensifier gate delay; focused ultrasound (FU) power; and imaging depth) and the image qualities (i.e., signal-to-noise ratio, spatial resolution, and temporal resolution). In this study, we also discussed several imaging strategies for achieving a high-quality USF image via this time-domain system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.