Evidence map›Paper›PMID 31332219›Full record

ArticleScientific reports2019

Stretchable Low Impedance Electrodes for Bioelectronic Recording from Small Peripheral Nerves.

Francesco Decataldo, Tobias Cramer, Davide Martelli, Isacco Gualandi, Willian S Korim, Song T Yao, Marta Tessarolo, Mauro Murgia, Erika Scavetta, Roberto Amici and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 74 citations in OpenAlex.

  1. Review
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  3. Article
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  7. Characterization of a Temporary Peripheral Nerve Stimulation Electrode Utilizing a Bioabsorbable Suture Substrate.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2022
    Article
  8. Article
  9. Review
  10. Flexible and Stretchable Bioelectronics.Materials (Basel, Switzerland) · 2022
    Review
  11. Review
  12. Article
  13. Article
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Francesco DecataldoDepartment of Physics and Astronomy, University of Bologna, Bologna, Italy.
Tobias CramerDepartment of Physics and Astronomy, University of Bologna, Bologna, Italy. tobias.cramer@unibo.it.ORCID http://orcid.org/0000-0002-5993-3388
Davide MartelliDepartment of Biomedical and Neuromotor Sciences - Physiology, University of Bologna, Bologna, Italy.
Isacco GualandiDepartment of Industrial Chemistry, University of Bologna, Bologna, Italy.
Willian S KorimFlorey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Australia.
Song T YaoFlorey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Australia.ORCID http://orcid.org/0000-0003-3337-4490
Marta TessaroloDepartment of Physics and Astronomy, University of Bologna, Bologna, Italy.
Mauro MurgiaInstituto per lo Studio dei Materiali Nanostrutturati (ISMN), Centro Nazionale delle Ricerche (CNR), Via Gobetti 101, 40129, Bologna, Italy.
Erika ScavettaDepartment of Industrial Chemistry, University of Bologna, Bologna, Italy.
Roberto AmiciDepartment of Biomedical and Neuromotor Sciences - Physiology, University of Bologna, Bologna, Italy.
Beatrice FraboniDepartment of Physics and Astronomy, University of Bologna, Bologna, Italy.
University of Bologna · ITThe University of Melbourne · AUGNA University · INInstitute of Nanostructured Materials · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monitoring of bioelectric signals in peripheral sympathetic nerves of small animal models is crucial to gain understanding of how the autonomic nervous system controls specific body functions related to disease states. Advances in minimally-invasive electrodes for such recordings in chronic conditions rely on electrode materials that show low-impedance ionic/electronic interfaces and elastic mechanical properties compliant with the soft and fragile nerve strands. Here we report a highly stretchable low-impedance electrode realized by microcracked gold films as metallic conductors covered with stretchable conducting polymer composite to facilitate ion-to-electron exchange. The conducting polymer composite based on poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) obtains its adhesive, low-impedance properties by controlling thickness, plasticizer content and deposition conditions. Atomic Force Microscopy measurements under strain show that the optimized conducting polymer coating is compliant with the micro-crack mechanics of the underlying Au-layer, necessary to absorb the tensile deformation when the electrodes are stretched. We demonstrate functionality of the stretchable electrodes by performing high quality recordings of renal sympathetic nerve activity under chronic conditions in rats.

Indexed as

Electrodes, ImplantedAnimalsBiosensing TechniquesElasticityElectric ImpedanceElectric StimulationKidneyMicroscopy, Atomic ForcePeripheral NervesPolystyrenesRatsRats, Sprague-DawleyThiophenespoly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate)PolystyrenesThiophenes

Identifiers

PMID31332219
PMCPMC6646361
OpenAlexW2962747317

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.