Evidence map›Paper›PMID 31332201›Full record

ReviewNature communications2019

Towards a standardized bioinformatics infrastructure for N- and O-glycomics.

Miguel A Rojas-Macias, Julien Mariethoz, Peter Andersson, Chunsheng Jin, Vignesh Venkatakrishnan, Nobuyuki P Aoki, Daisuke Shinmachi, Christopher Ashwood, Katarina Madunic, Tao Zhang and 14 more

Abstract readReview
In one paragraph

Review in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Glycoscience data content in the NCBI Glycans and PubChem.Analytical and bioanalytical chemistry · 2025
    Article
  8. Article
  9. Review
  10. Exploring the O-glycomic Degradome Using Natural Mucin Libraries.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. UniCarb-DB: An MS/MS Experimental Glycomic Fragmentation Database.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  15. Article
  16. Article
  17. Identification of the High MannoseAnalytical chemistry · 2023
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Miguel A Rojas-MaciasDepartment of Medical Biochemistry and Cell Biology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.
Julien MariethozProteome Informatics Group, SIB Swiss Institute of Bioinformatics, Geneva, 1211, Switzerland.ORCID http://orcid.org/0000-0001-8974-4417
Peter AnderssonDepartment of Medical Biochemistry and Cell Biology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.
Chunsheng JinDepartment of Medical Biochemistry and Cell Biology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.
Vignesh VenkatakrishnanDepartment of Medical Biochemistry and Cell Biology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.ORCID http://orcid.org/0000-0001-5671-1547
Nobuyuki P AokiSoka University, Hachioji, 192-8577, Tokyo, Japan.
Daisuke ShinmachiSoka University, Hachioji, 192-8577, Tokyo, Japan.ORCID http://orcid.org/0000-0002-2591-3987
Christopher AshwoodDepartment of Molecular Sciences, Macquarie University, Sydney, 2109, Australia.ORCID http://orcid.org/0000-0001-5944-6179
Katarina MadunicLeiden University Medical Center, Leiden, 2333ZA, Netherlands.ORCID http://orcid.org/0000-0002-9310-4110
Tao ZhangLeiden University Medical Center, Leiden, 2333ZA, Netherlands.
Rebecca L MillerCopenhagen Centre for Glycomics, Department of Cellular and Molecular Medicine, University of Copenhagen, København, DK-2200, Denmark.ORCID http://orcid.org/0000-0001-8574-1948
Oliver HorlacherProteome Informatics Group, SIB Swiss Institute of Bioinformatics, Geneva, 1211, Switzerland.
Weston B StruweDepartment of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, OX1 3TA, UK.
Yu WatanabeGraduate School of Medical and Dental Sciences, Niigata University, 950-2181, Niigata, Japan.
Shujiro OkudaGraduate School of Medical and Dental Sciences, Niigata University, 950-2181, Niigata, Japan.ORCID http://orcid.org/0000-0002-7704-8104
Fredrik LevanderNational Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Department of Immunotechnology, Lund University, Lund, 22387, Sweden.ORCID http://orcid.org/0000-0002-0710-9792
Daniel KolarichInstitute for Glycomics, Gold Coast Campus, Griffith University, Gold Coast, QLD, QLD 4222, Australia.ORCID http://orcid.org/0000-0002-8452-1350
Pauline M RuddBioprocessing Technology Institute, AStar, Singapore, 138668, Singapore.
Manfred WuhrerLeiden University Medical Center, Leiden, 2333ZA, Netherlands.
Carsten KettnerBeilstein-Institut, Frankfurt am Main, 60487, Germany.ORCID http://orcid.org/0000-0002-8697-6842
Nicolle H PackerDepartment of Molecular Sciences, Macquarie University, Sydney, 2109, Australia.ORCID http://orcid.org/0000-0002-7532-4021
Kiyoko F Aoki-KinoshitaSoka University, Hachioji, 192-8577, Tokyo, Japan.ORCID http://orcid.org/0000-0002-6662-8015
Frédérique LisacekProteome Informatics Group, SIB Swiss Institute of Bioinformatics, Geneva, 1211, Switzerland.ORCID http://orcid.org/0000-0002-0948-4537
Niclas G KarlssonDepartment of Medical Biochemistry and Cell Biology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden. niclas.karlsson@medkem.gu.se.ORCID http://orcid.org/0000-0002-3045-2628

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mass spectrometry (MS)-based analysis of free polysaccharides and glycans released from proteins, lipids and proteoglycans increasingly relies on databases and software. Here, we review progress in the bioinformatics analysis of protein-released N- and O-linked glycans (N- and O-glycomics) and propose an e-infrastructure to overcome current deficits in data and experimental transparency. This workflow enables the standardized submission of MS-based glycomics information into the public repository UniCarb-DR. It implements the MIRAGE (Minimum Requirement for A Glycomics Experiment) reporting guidelines, storage of unprocessed MS data in the GlycoPOST repository and glycan structure registration using the GlyTouCan registry, thereby supporting the development and extension of a glycan structure knowledgebase.

Indexed as

AnimalsComputational BiologyDatabases, FactualGlycomicsGlycoproteinsHumansMass SpectrometryPolysaccharidesReference StandardsGlycoproteinsPolysaccharides

Identifiers

PMID31332201
PMCPMC6796180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.