Evidence map›Paper›PMID 31332077›Full record

ArticleAntimicrobial agents and chemotherapy2019

The TetR Family Transcription Factor MAB_2299c Regulates the Expression of Two Distinct MmpS-MmpL Efflux Pumps Involved in Cross-Resistance to Clofazimine and Bedaquiline in Mycobacterium abscessus.

Ana Victoria Gutiérrez, Matthias Richard, Françoise Roquet-Banères, Albertus Viljoen, Laurent Kremer

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Journal of bacteriology · 2026
    Review
  3. Article
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  5. Article
  6. Review
  7. Article
  8. Article
  9. Novel mutations in theAntimicrobial agents and chemotherapy · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Efflux pump effects on levofloxacin resistance inAntimicrobial agents and chemotherapy · 2024
    Article
  15. Exploring antibiotic resistance mechanisms inFrontiers in microbiology · 2024
    Review
  16. Article
  17. Evolution ofVirulence · 2023
    Article
  18. Review
  19. Drug susceptibility distributions ofAntimicrobial agents and chemotherapy · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ana Victoria Gutiérrez *Institut de Recherche en Infectiologie de Montpellier (IRIM), Université de Montpellier, CNRS UMR 9004, Montpellier, France.
Matthias Richard *Institut de Recherche en Infectiologie de Montpellier (IRIM), Université de Montpellier, CNRS UMR 9004, Montpellier, France.
Françoise Roquet-BanèresInstitut de Recherche en Infectiologie de Montpellier (IRIM), Université de Montpellier, CNRS UMR 9004, Montpellier, France.
Albertus ViljoenInstitut de Recherche en Infectiologie de Montpellier (IRIM), Université de Montpellier, CNRS UMR 9004, Montpellier, France.ORCID 0000-0001-8949-7401
Laurent KremerInstitut de Recherche en Infectiologie de Montpellier (IRIM), Université de Montpellier, CNRS UMR 9004, Montpellier, France laurent.kremer@irim.cnrs.fr.ORCID 0000-0002-6604-4458
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antitubercular AgentsBacterial ProteinsClofazimineDiarylquinolinesDrug Resistance, BacterialElectrophoretic Mobility Shift AssayGene Expression RegulationHumansMicrobial Sensitivity TestsMycobacterium abscessusReal-Time Polymerase Chain ReactionTHP-1 CellsTranscription FactorsAntitubercular AgentsBacterial ProteinsbedaquilineClofazimineDiarylquinolinesTranscription Factorsbedaquilineclofaziminedrug resistance mechanismsefflux pumpsEMSAMmpLMycobacterium abscessusTetR regulator

Identifiers

PMID31332077
PMCPMC6761555
OpenAlexW2963985285

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.