Evidence map›Paper›PMID 31332039›Full record

ArticleDevelopment (Cambridge, England)2019

The lymphoid-associated interleukin 7 receptor (IL7R) regulates tissue-resident macrophage development.

Gabriel A Leung, Taylor Cool, Clint H Valencia, Atesh Worthington, Anna E Beaudin, E Camilla Forsberg

Open access · greenAbstract read
In one paragraph

Article in Development (Cambridge, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 75 citations in OpenAlex.

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  16. The emerging family of RORγtNature reviews. Immunology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Gabriel A LeungQuantitative and Systems Biology Program, University of California-Merced, Merced, CA 95343, USA.
Taylor CoolInstitute for the Biology of Stem Cells, University of California-Santa Cruz, Santa Cruz, CA 95064, USA.
Clint H ValenciaMolecular and Cell Biology Department, School of Natural Sciences, University of California-Merced, Merced, CA 95343, USA.
Atesh WorthingtonInstitute for the Biology of Stem Cells, University of California-Santa Cruz, Santa Cruz, CA 95064, USA.
Anna E BeaudinMolecular and Cell Biology Department, School of Natural Sciences, University of California-Merced, Merced, CA 95343, USA abeaudin@ucmerced.edu cforsber@ucsc.edu.ORCID 0000-0002-8580-8660
E Camilla ForsbergInstitute for the Biology of Stem Cells, University of California-Santa Cruz, Santa Cruz, CA 95064, USA abeaudin@ucmerced.edu cforsber@ucsc.edu.ORCID 0000-0003-0715-9703
University of California, Merced · USUniversity of California, Santa Cruz · US

Funding

Role and Regulation of a Novel, Developmentally Restricted Hematopoietic Stem CellR01DK100917 · NIDDK · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI FORSBERG, CAMILLA · 2013 to 2024
$3.9M
Training Program/Molecular/Cell/Developmental BiologyT32GM008646 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI STROME, SUSAN · 1999 to 2018
$3.7M
Regulation of tissue resident macrophage development by IL-7R signalingR01HL147081 · NHLBI · UNIVERSITY OF UTAH · PI BEAUDIN, ANNA E · 2019 to 2023
$1.8M
Contributio of a novel developmentally-restricted hematopoietic stem cellK01HL130753 · NHLBI · UNIVERSITY OF UTAH · PI BEAUDIN, ANNA E · 2016 to 2020
$891k
MESOTHELIAL MECHANOTRANSDUCTION AS A KEY REGULATOR OF EMBRYONIC LUNG GROWTHF31HL140781 · NHLBI · UNIVERSITY OF DELAWARE · PI GILBERT, RACHEL · 2018 to 2021
$107k
NHLBI NIH HHS F31 HL140781NHLBI NIH HHS K01 HL130753NHLBI NIH HHS R01 HL147081NIDDK NIH HHS R01 DK100917NIGMS NIH HHS T32 GM008646
6 · The paper itself

Abstract

The discovery of a fetal origin for tissue-resident macrophages (trMacs) has inspired an intense search for the mechanisms underlying their development. Here, we performed

Indexed as

AnimalsCell DifferentiationCell LineageEmbryo, MammalianFemaleFetusHematopoiesisMacrophagesMaleMiceMice, Inbred C57BLMice, TransgenicMyelopoiesisPregnancyReceptors, Interleukin-7interleukin-7 receptor, alpha chainReceptors, Interleukin-7Developmental hematopoiesisHematopoietic stem cellsIL7RLineage tracingMonocyte to macrophage differentiationMouseTissue-resident macrophages

Identifiers

PMID31332039
PMCPMC6679362
OpenAlexW2964263062

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.