Evidence map›Paper›PMID 31332037›Full record

ReviewDevelopment (Cambridge, England)2019

Model systems for regeneration: salamanders.

Alberto Joven, Ahmed Elewa, András Simon

Open access · bronzeAbstract readReview
In one paragraph

Review in Development (Cambridge, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

103 citing papers in PubMed, 188 citations in OpenAlex.

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  16. The Immunologic Spectrum of Biostimulators and Its Clinical Importance.Plastic and reconstructive surgery. Global open · 2025
    Article
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  19. Article
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43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Alberto JovenKarolinska Institute, Department of Cell and Molecular Biology, Biomedicum, Solnavägen 9, 17163 Stockolm, Sweden.ORCID 0000-0002-0926-4665
Ahmed ElewaKarolinska Institute, Department of Cell and Molecular Biology, Biomedicum, Solnavägen 9, 17163 Stockolm, Sweden andras.simon@ki.se aelewa@cshl.edu.ORCID 0000-0002-1988-7970
András SimonKarolinska Institute, Department of Cell and Molecular Biology, Biomedicum, Solnavägen 9, 17163 Stockolm, Sweden andras.simon@ki.se aelewa@cshl.edu.ORCID 0000-0002-1018-1891
Karolinska Institutet · SE

Funding

Discovering signature genes and developing expression markers for blastema cellsF32GM117806 · NIGMS · KAROLINSKA INSTITUTE · PI ELEWA, AHMED · 2016 to 2018
$171k
NIGMS NIH HHS F32 GM117806
6 · The paper itself

Abstract

Salamanders have been hailed as champions of regeneration, exhibiting a remarkable ability to regrow tissues, organs and even whole body parts, e.g. their limbs. As such, salamanders have provided key insights into the mechanisms by which cells, tissues and organs sense and regenerate missing or damaged parts. In this Primer, we cover the evolutionary context in which salamanders emerged. We outline the varieties of mechanisms deployed during salamander regeneration, and discuss how these mechanisms are currently being explored and how they have advanced our understanding of animal regeneration. We also present arguments about why it is important to study closely related species in regeneration research.

Indexed as

Models, AnimalModels, BiologicalAnimalsBiological EvolutionBiomedical ResearchCaudataHumansRegenerationRegenerative MedicineAxolotlCNSGenomeLimbModel organismNewt

Identifiers

PMID31332037
PMCPMC6679358
OpenAlexW2964195156

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.