ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019
Development of Human Emotion Circuits Investigated Using a Big-Data Analytic Approach: Stability, Reliability, and Robustness.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A coordinate-based meta-analysis of human amygdala connectivity alterations related to early life adversities.Scientific reports · 2023Pooled it
- Biological aging in childhood and adolescence following experiences of threat and deprivation: A systematic review and meta-analysis.Psychological bulletin · 2020Pooled it
- Gut microbiota remodeling and sensory-emotional functional disruption in adolescents with bipolar depression.Journal of translational medicine · 2025Trial
- Acupuncture modulates emotional network resting-state functional connectivity in patients with insomnia disorder: a randomized controlled trial and fMRI study.BMC complementary medicine and therapies · 2024Trial
- Environmental, Health, and Psychological Factors Predict Alcohol Sipping in Childhood: A Machine Learning Analysis of the ABCD Study.JAACAP open · 2025Article
- Associations Between Neighborhood Resources and Youths' Response to Reward Omission in a Task Modeling Negatively Biased Environments.Journal of the American Academy of Child and Adolescent Psychiatry · 2025Article
- Age- and sex-related differences in social competence and emotion labeling in pre-adolescence.Developmental cognitive neuroscience · 2025Article
- Associations between parental psychopathology and youth functional emotion regulation brain networks.Developmental cognitive neuroscience · 2024Article
- The role of functional emotion circuits in distinct dimensions of psychopathology in youth.Translational psychiatry · 2024Article
- The Left Amygdala and Right Frontoparietal Cortex Support Emotional Adaptation Aftereffects.Brain sciences · 2024Article
- A Bayesian incorporated linear non-Gaussian acyclic model for multiple directed graph estimation to study brain emotion circuit development in adolescence.Network neuroscience (Cambridge, Mass.) · 2024Article
- Structural brain changes in emotion recognition across the adult lifespan.Social cognitive and affective neuroscience · 2023Article
- Somatovisceral influences on emotional development.Emotion review : journal of the International Society for Research on Emotion · 2023Article
- Decoding six basic emotions from brain functional connectivity patterns.Science China. Life sciences · 2023Article
- Age-related change in task-evoked amygdala-prefrontal circuitry: A multiverse approach with an accelerated longitudinal cohort aged 4-22 years.Human brain mapping · 2022Article
- Audio and visual speech emotion activate the left pre-supplementary motor area.Cognitive, affective & behavioral neuroscience · 2022Article
- Neural Connectivity Underlying Reward and Emotion-Related Processing: Evidence From a Large-Scale Network Analysis.Frontiers in systems neuroscience · 2022Article
- Mechanisms of neuroplasticity linking early adversity to depression: developmental considerations.Translational psychiatry · 2021Review
- Characterizing the Network Architecture of Emotion Regulation Neurodevelopment.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Interactions between methodological and interindividual variability: How Monetary Incentive Delay (MID) task contrast maps vary and impact associations with behavior.Brain and behavior · 2021Article
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4 authors.
Funding
Abstract
Emotion perception is fundamental to affective and cognitive development and is thought to involve distributed brain circuits. Efforts to chart neurodevelopmental changes in emotion have been severely hampered by narrowly focused approaches centered on activation of individual brain regions and small sample sizes. Here we investigate the maturation of human functional brain circuits associated with identification of fearful, angry, sad, happy, and neutral faces using a large sample of 759 children, adolescents, and adults (ages 8-23; female/male = 419/340). Network analysis of emotion-related brain circuits revealed three functional modules, encompassing lateral frontoparietal, medial prefrontal-posterior cingulate, and subcortical-posterior insular cortices, with hubs in medial prefrontal, but not posterior cingulate, cortex. This overall network architecture was stable by age 8, and it anchored maturation of circuits important for salience detection and cognitive control, as well as dissociable circuit patterns across distinct emotion categories. Our findings point to similarities and differences in functional circuits associated with identification of fearful, angry, sad, happy, and neutral faces, and reveal aspects of brain circuit organization underlying emotion perception that are stable over development as well as features that change with age. Reliability analyses demonstrated the robustness of our findings and highlighted the importance of large samples for probing functional brain circuit development. Our study emphasizes a need to focus beyond amygdala circuits and provides a robust neurodevelopmental template for investigating emotion perception and identification in psychopathology.
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