Evidence map›Paper›PMID 31331964›Full record

ArticleJournal of cell science2019

Sirtuin 7 promotes 45S pre-rRNA cleavage at site 2 and determines the processing pathway.

Valentina Sirri, Alice Grob, Jérémy Berthelet, Nathalie Jourdan, Pascal Roussel

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cell science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. SNORD80-guided 2'-O-methylation stabilizes the lncRNA GAS5 to regulate cellular stress responses.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Protein acetylation: a novel modus of obesity regulation.Journal of molecular medicine (Berlin, Germany) · 2021
    Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Valentina SirriUniversité de Paris, Unité de Biologie Fonctionnelle et Adaptative (BFA), UMR 8251, CNRS, 4 rue Marie-Andrée Lagroua Weill-Hallé, F-75013 Paris, France.
Alice GrobDepartment of Life Sciences, Imperial College London, London SW7 2AZ, England, UK.
Jérémy BertheletUniversité de Paris, Unité de Biologie Fonctionnelle et Adaptative (BFA), UMR 8251, CNRS, 4 rue Marie-Andrée Lagroua Weill-Hallé, F-75013 Paris, France.
Nathalie JourdanSorbonne Université, Institut de Biologie Paris-Seine (IBPS), UMR 8256, CNRS, 9 quai St Bernard, F-75005 Paris, France.
Pascal RousselUniversité de Paris, Unité de Biologie Fonctionnelle et Adaptative (BFA), UMR 8251, CNRS, 4 rue Marie-Andrée Lagroua Weill-Hallé, F-75013 Paris, France p.roussel@univ-paris-diderot.fr.ORCID 0000-0002-3093-669X
Centre National de la Recherche Scientifique · FRImperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In humans, ribosome biogenesis mainly occurs in nucleoli following two alternative pre-rRNA processing pathways differing in the order in which cleavages take place but not by the sites of cleavage. To uncover the role of the nucleolar NAD

Indexed as

BenzamidesCatalytic DomainChromosomal Proteins, Non-HistoneHEK293 CellsHeLa CellsHumansNaphtholsNuclear ProteinsOrganelle BiogenesisRibosomesRNA, RibosomalRNA, Small InterferingSirtuinsBenzamidesChromosomal Proteins, Non-HistonefibrillarinNaphtholsNOP56 protein, humanNuclear ProteinsRNA, RibosomalRNA, ribosomal, 45SRNA, Small InterferingSIRT7 protein, humansirtinolSirtuinsDeacetylaseNucleolusPre-rRNA processingRibosomeSIRT7Sirtinol

Identifiers

PMID31331964
PMCPMC6771141
OpenAlexW2963923200

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.