Evidence map›Paper›PMID 31331956›Full record

ArticleInfection and immunity2019

Iron-Sulfur Cluster Repair Contributes to Yersinia pseudotuberculosis Survival within Deep Tissues.

Kimberly M Davis, Joanna Krupp, Stacie Clark, Ralph R Isberg

Open access · hybridAbstract read
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. NO-StressedInfection and immunity · 2022
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Sulfur Administration in Fe-S Cluster Homeostasis.Antioxidants (Basel, Switzerland) · 2021
    Review
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kimberly M DavisDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA kdavi140@jhu.edu.
Joanna KruppDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.
Stacie ClarkDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.
Ralph R IsbergDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.
Tufts University · US

Funding

Mammalian cell collaboration with bacterial type III secretionR01AI110684 · NIAID · TUFTS UNIVERSITY BOSTON · PI ISBERG, RALPH R. · 2016 to 2020
$2.1M
Community behavior of Yersinia pseudotuberculosis within microcoloniesK22AI123465 · NIAID · JOHNS HOPKINS UNIVERSITY · PI DAVIS, KIM · 2017 to 2018
$270k
NIAID NIH HHS K22 AI123465NIAID NIH HHS R01 AI110684
6 · The paper itself

Abstract

To successfully colonize host tissues, bacteria must respond to and detoxify many different host-derived antimicrobial compounds, such as nitric oxide (NO). NO has direct antimicrobial activity through attack on iron-sulfur (Fe-S) cluster-containing proteins. NO detoxification plays an important role in promoting bacterial survival, but it remains unclear if repair of Fe-S clusters is also important for bacterial survival within host tissues. Here we show that the Fe-S cluster repair protein YtfE contributes to the survival of

Indexed as

AnimalsBacterial ProteinsFemaleGene DeletionGene ExpressionHost-Pathogen InteractionsIron-Sulfur ProteinsMiceMice, Inbred C57BLMicrobial ViabilityNADH, NADPH OxidoreductasesNitric OxideSpleenYersinia pseudotuberculosisYersinia pseudotuberculosis InfectionsBacterial ProteinsIron-Sulfur ProteinsNADH, NADPH OxidoreductasesNitric Oxideiron-sulfur cluster repairnitric oxideYersinia pseudotuberculosis

Identifiers

PMID31331956
PMCPMC6759291
OpenAlexW2964260467

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.