Evidence map›Paper›PMID 31331935›Full record

ArticleThe Journal of biological chemistry2019

Insights into the catalytic mechanism of a bacterial hydrolytic dehalogenase that degrades the fungicide chlorothalonil.

Xinhang Yang, Brian Bennett, Richard C Holz

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Xinhang YangDepartment of Chemistry, Marquette University, Milwaukee, Wisconsin 53201-1881.
Brian BennettDepartment of Physics, Marquette University, Milwaukee, Wisconsin 53233.
Richard C HolzDepartment of Chemistry, Marquette University, Milwaukee, Wisconsin 53201-1881; Department of Chemistry, Colorado School of Mines, Golden, Colorado 80401. Electronic address: rholz@mines.edu.
Marquette University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chlorothalonil (2,4,5,6-tetrachloroisophtalonitrile; TPN) is one of the most commonly used fungicides in the United States. Given TPN's widespread use, general toxicity, and potential carcinogenicity, its biodegradation has garnered significant attention. Here, we developed a direct spectrophotometric assay for the Zn(II)-dependent, chlorothalonil-hydrolyzing dehalogenase from

Indexed as

BiocatalysisFungicides, IndustrialHydrolasesHydrolysisMolecular StructureNitrilesPseudomonasFungicides, Industrialhaloalkane dehalogenaseHydrolasesNitrilestetrachloroisophthalonitrilebioremediationChdchlorothalonildehalogenaseenzyme catalysisenzyme kineticsenzyme mechanismhydrolasestopped-flowzinc

Identifiers

PMID31331935
PMCPMC6737215
OpenAlexW2963327059

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.