Evidence map›Paper›PMID 31331919›Full record

Trial reportBlood2019

Adjuvant low-dose rituximab and plasma exchange for acquired TTP.

Jeffrey I Zwicker, Joshua Muia, Leili Dolatshahi, Lisa A Westfield, Patricia Nieters, Anita Rodrigues, Ayad Hamdan, Ana G Antun, Ara Metjian, J Evan Sadler and 1 more

Abstract readClinical Trial, Phase IILetterMulticenter Study
In one paragraph

Trial report in Blood, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Tailored treatment of acute immune-mediated thrombotic thrombocytopenic purpura.Hematology. American Society of Hematology. Education Program · 2025
    Review
  5. Thrombotic thrombocytopaenic purpura.European heart journal. Case reports · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Comparison of Clinical Scoring Systems in the Management of Patients with Microangiopathic Hemolytic Anemia and ThrombocytopeniaTurkish journal of haematology : official journal of Turkish Society of Haematology · 2021
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jeffrey I ZwickerDivision of Hematology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.ORCID 0000-0001-5810-6893
Joshua MuiaDepartment of Medicine, Washington University School of Medicine, St. Louis, MO.ORCID 0000-0001-5011-2420
Leili DolatshahiDivision of Pediatric Hematology, Saint Louis University School of Medicine, St. Louis, MO.
Lisa A WestfieldDepartment of Medicine, Washington University School of Medicine, St. Louis, MO.
Patricia NietersWashington University Institute of Clinical and Translational Sciences, Washington University School of Medicine, St. Louis, MO.
Anita RodriguesDivision of Hematology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.
Ayad HamdanDivision of Hematology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.
Ana G AntunDepartment of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA.
Ara MetjianDivision of Hematology, Duke University School of Medicine, Durham, NC; and.
J Evan SadlerDepartment of Medicine, Washington University School of Medicine, St. Louis, MO.ORCID 0000-0001-5705-469X
ART Investigators

Funding

Training In Cardiovascular Physiology & PharmacologyT32HL007444 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ju Chen, Robert Scott Ross · 1985 to 2026
$11.1M
Translational Research Skills Development CoreU54HL112303 · NHLBI · WASHINGTON UNIVERSITY · PI SADLER, J EVAN · 2012 to 2016
$8.8M
UCSD PRIDE Faculty Development Program in Cardiovascular SciencesR25HL145817 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Robert Scott Ross, Joann Trejo · 2019 to 2026
$3.3M
NHLBI NIH HHS R25 HL145817NHLBI NIH HHS T32 HL007444NHLBI NIH HHS U54 HL112303
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Plasma ExchangeFemaleHumansImmunologic FactorsMaleMiddle AgedPurpura, Thrombotic ThrombocytopenicRituximabTreatment OutcomeImmunologic FactorsRituximab

Identifiers

PMID31331919
PMCPMC6764263

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.