ArticleThe Lancet. Global health2019
Socioeconomic determinants of leprosy new case detection in the 100 Million Brazilian Cohort: a population-based linkage study.
Article in The Lancet. Global health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 6 of them syntheses that pooled it.
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62 citing papers in PubMed, 6 syntheses or guidelines pooled it, 174 citations in OpenAlex.
- Leprosy in skeletons from archaeological sites: A systematic review.PLoS neglected tropical diseases · 2025Pooled it
- Prevalence of paucibacillary cases of leprosy in Brazil: a 20-year systematic review and meta-analysis.Frontiers in medicine · 2024Pooled it
- Comparative analysis of the leprosy detection rate regarding its clinical spectrum through PCR using theFrontiers in microbiology · 2024Pooled it
- Prevalence of plantar ulcer and its risk factors in leprosy: a systematic review and meta-analysis.Journal of foot and ankle research · 2023Pooled it
- Experiences of living with leprosy: A systematic review and qualitative evidence synthesis.PLoS neglected tropical diseases · 2022Pooled it
- Prevalence of Mycobacterium leprae in armadillos in Brazil: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2020Pooled it
- Trial
- The intersecting effects of race/ethnicity, wealth, education, and gender on AIDS among 28.3 million Brazilians.Nature communications · 2026Article
- Lessons From the Past, Hope for the Future: A Qualitative Study on the Lives of Leprosy-Affected Residents of a Leprosy Settlement in Malaysia.Qualitative health research · 2026Article
- Seroprevalence ofThe Lancet regional health. Southeast Asia · 2026Article
- Biosensor-Based Platforms for the Detection and Screening ofACS infectious diseases · 2026Review
- Autoantibodies and vitamin D in leprosy patients in the Brazilian Amazon.BMC infectious diseases · 2026Article
- Integrated strategies for controlling and eliminating Neglected Tropical Diseases in Sub-Saharan Africa: a review of approaches, challenges, and opportunities.Tropical diseases, travel medicine and vaccines · 2026Review
- Article
- Temporal trend and factors associated with physical disability due to leprosyl: a time series study, Brazil, 2014-2023.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2026Article
- Associated Factors of Mycobacterium Leprae Infection among People with Leprosy in Kwale County.PLoS neglected tropical diseases · 2025Article
- The Minha Casa Minha Vida social housing programme and leprosy in Brazil: an analysis of the 100 Million Brazilian Cohort (2010-2015).BMC public health · 2025Article
- Evaluating Machine Learning Models for Predicting Late Leprosy Diagnosis by Physical Disability Grade in Brazil (2018-2022).Tropical medicine and infectious disease · 2025Article
- Wildlife hunting and the increased risk of leprosy transmission in the tropical Americas: a pathogeographical study.Infectious diseases of poverty · 2025Article
- Time trend and identification of risk areas for physical disability due to leprosy in Brazil: An ecological study, 2001-2022.BMC infectious diseases · 2025Article
2 more citing papers are in PubMed but not listed here.
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Authors and funding
12 authors at 6 institutions in 2 countries.
Funding
Abstract
backgroundAlthough leprosy is recognised as a disease of poverty, there is little evidence on the specific socioeconomic factors associated with disease risk. To inform targeted strategies for disease elimination, we investigated socioeconomic markers of leprosy risk in Brazil.
methodsSocioeconomic data from the 100 Million Brazilian Cohort were linked to the Brazilian national disease registry (Sistema de Informação de Agravos de Notificação) for leprosy from Jan 1, 2007, to Dec 31, 2014. Using Poisson regression, we assessed the association of socioeconomic factors with risk of incident leprosy in the full cohort and in children (aged 0-15 years), by leprosy subtype and region of residence.
findingsIn an analysis of 23 899 942 individuals including 18 518 patients with leprosy, increased levels of deprivation were associated with an increased risk of leprosy in Brazil. Directions of effect were consistent in children younger than 15 years and across disease subtypes. Individuals residing in regions with the highest poverty in the country (central-west, north, and northeast regions) had a risk of leprosy incidence five-to-eight times greater than did other individuals. Decreased levels of income and education and factors reflecting unfavourable living conditions were associated with an up to two-times increase in leprosy incidence (incidence rate ratio 1·46, 95% CI 1·32-1·62, for lowest vs highest quartile of income per capita; 2·09, 95% CI 1·62-2·72, for lowest vs highest level of education).
interpretationWithin the poorest half of the Brazilian population, the most deprived individuals have the greatest risk of leprosy. Strategies focusing on early detection and treatment in the poorest populations could contribute substantially to global disease control.
fundingMedical Research Council, Wellcome Trust, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Brazil), the Conselho Nacional das Fundações Estaduais de Amparo à Pesquisa, Economic and Social Research Council, Biotechnology and Biological Sciences Research Council, Conselho Nacional de Desenvolvimento Científico e Tecnológico, and Fundação de Apoio à Pesquisa do Distrito Federal.
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