ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2019
Multipoint 5D flow cardiovascular magnetic resonance - accelerated cardiac- and respiratory-motion resolved mapping of mean and turbulent velocities.
Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.
- Evaluation of intraventricular flow by multimodality imaging: a review and meta-analysis.Cardiovascular ultrasound · 2021Pooled it
- Fully self-gated dual-venc five-dimensional flow magnetic resonance imaging for simultaneous imaging of the cardiovascular and portal venous systems: A feasibility study.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2026Article
- 4D Flow MRI at 0.6 T-Self-Gating Versus Camera-Based Respiratory Binning.Bioengineering (Basel, Switzerland) · 2026Article
- Real-time 4D MRI reconstruction using DVR-NeMF, a framework for dynamic volumetric reconstruction.Cell reports methods · 2025Article
- Artificial Intelligence and Augmented Reality in Vascular Neurosurgery.Acta neurochirurgica. Supplement · 2025Article
- Optimizing encoding strategies for 4D Flow MRI of mean and turbulent flow.Scientific reports · 2024Article
- K-t PCA accelerated in-plane balanced steady-state free precession phase-contrast (PC-SSFP) for all-in-one diastolic function evaluation.Magnetic resonance in medicine · 2024Article
- 4D Flow cardiovascular magnetic resonance consensus statement: 2023 update.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023Review
- Focused navigation for respiratory-motion-corrected free-running radial 4D flow MRI.Magnetic resonance in medicine · 2023Article
- Latest Advances in Image Acceleration: All Dimensions are Fair Game.Journal of magnetic resonance imaging : JMRI · 2023Review
- Non-invasive cardiovascular magnetic resonance assessment of pressure recovery distance after aortic valve stenosis.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023Article
- Atrial cardiomyopathy: Current and future imaging methods for assessment of atrial structure and function.Frontiers in cardiovascular medicine · 2023Review
- Free-breathing motion-informed locally low-rank quantitative 3D myocardial perfusion imaging.Magnetic resonance in medicine · 2022Article
- Inverse problems in blood flow modeling: A review.International journal for numerical methods in biomedical engineering · 2022Review
- Echo planar imaging-induced errors in intracardiac 4D flow MRI quantification.Magnetic resonance in medicine · 2022Article
- 4D Flow MR Imaging of the Left Atrium: What is Non-physiological Blood Flow in the Cardiac System?Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2022Article
- Fundamentals of turbulent flow spectrum imaging.Magnetic resonance in medicine · 2022Article
- Pilot tone navigation for respiratory and cardiac motion-resolved free-running 5D flow MRI.Magnetic resonance in medicine · 2022Article
- Simultaneous multi-parametric acquisition and reconstruction techniques in cardiac magnetic resonance imaging: Basic concepts and status of clinical development.Frontiers in cardiovascular medicine · 2022Review
- Dos and don'ts in large animal models of aortic insufficiency.Frontiers in veterinary science · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVolumetric quantification of mean and fluctuating velocity components of transient and turbulent flows promises a comprehensive characterization of valvular and aortic flow characteristics. Data acquisition using standard navigator-gated 4D Flow cardiovascular magnetic resonance (CMR) is time-consuming and actual scan times depend on the breathing pattern of the subject, limiting the applicability of the method in a clinical setting. We sought to develop a 5D Flow CMR framework which combines undersampled data acquisition including multipoint velocity encoding with low-rank image reconstruction to provide cardiac- and respiratory-motion resolved assessment of velocity maps and turbulent kinetic energy in fixed scan times.
methodsData acquisition and data-driven motion state detection was performed using an undersampled Cartesian tiny Golden angle approach. Locally low-rank (LLR) reconstruction was implemented to exploit correlations among heart phases and respiratory motion states. To ensure accurate quantification of mean and turbulent velocities, a multipoint encoding scheme with two velocity encodings per direction was incorporated. Velocity-vector fields and turbulent kinetic energy (TKE) were obtained using a Bayesian approach maximizing the posterior probability given the measured data. The scan time of 5D Flow CMR was set to 4 min. 5D Flow CMR with acceleration factors of 19 .0 ± 0.21 (mean ± std) and velocity encodings (VENC) of 0.5 m/s and 1.5 m/s per axis was compared to navigator-gated 2x SENSE accelerated 4D Flow CMR with VENC = 1.5 m/s in 9 subjects. Peak velocities and peak flow were compared and magnitude images, velocity and TKE maps were assessed.
resultsWhile net scan time of 5D Flow CMR was 4 min independent of individual breathing patterns, the scan times of the standard 4D Flow CMR protocol varied depending on the actual navigator gating efficiency and were 17.8 ± 3.9 min on average. Velocity vector fields derived from 5D Flow CMR in the end-expiratory state agreed well with data obtained from the navigated 4D protocol (normalized root-mean-square error 8.9 ± 2.1%). On average, peak velocities assessed with 5D Flow CMR were higher than for the 4D protocol (3.1 ± 4.4%).
conclusionsRespiratory-motion resolved multipoint 5D Flow CMR allows mapping of mean and turbulent velocities in the aorta in 4 min.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.