ArticleBMC women's health2019
Growth pattern of uterine leiomyoma along pregnancy.
Article in BMC women's health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- The effects and costs of laparoscopic versus abdominal myomectomy in patients with uterine fibroids: a systematic review and meta-analysis.BMC surgery · 2020Pooled it
- Natural history of fibroids in pregnancy: National Institute of Child Health and Human Development Fetal Growth Studies - Singletons cohort.Fertility and sterility · 2022Trial
- Management of atypical complicated abdominal masses in the second trimester of pregnancy.BMJ case reports · 2026Article
- UTERINE FIBROIDS.Physiological reviews · 2025Review
- The characteristics of a fibroid in pregnancy can influence the perinatal outcome.Archives of gynecology and obstetrics · 2024Article
- Unexpected early pregnancy during myomectomy followed by successful term delivery: A case report.International journal of reproductive biomedicine · 2024Article
- Multiparametric quantitative magnetic resonance imaging of uterine fibroids for prediction of growth rate-a pilot study.Quantitative imaging in medicine and surgery · 2024Article
- Cotyledonoid dissecting leiomyoma of the uterus: a case report and review of the literature.Journal of medical case reports · 2023Review
- Associations of Pregnancy Per- and Polyfluoroalkyl Substance Concentrations and Uterine Fibroid Changes across Pregnancy: NICHD Fetal Growth Studies - Singletons Cohort.Environmental health perspectives · 2023Article
- Uterine Fibroids Causing Preterm Birth: A New Pathophysiological Hypothesis on the Role of Fibroid Necrosis and Inflammation.International journal of molecular sciences · 2022Article
- Role of Ultrasound in the Assessment and Differential Diagnosis of Pelvic Pain in Pregnancy.Diagnostics (Basel, Switzerland) · 2022Review
- Article
- Cytogenomic Profile of Uterine Leiomyoma: In Vivo vs. In Vitro Comparison.Biomedicines · 2021Article
- Intelligent Noise Reduction Algorithm to Evaluate the Correlation between Human Fat Deposits and Uterine Fibroids under Ultrasound Imaging.Journal of healthcare engineering · 2021Article
- The role of magnetic resonance-guided focused ultrasound in fertility-sparing treatment of uterine fibroids-current perspectives.Ecancermedicalscience · 2020Article
- Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUterine leiomyomas are often discovered during early pregnancy and in most cases will have no effect on pregnancy outcomes. However, in rare cases uterine leiomyomas may lead to obstetric complications. The aim of the study was to evaluate rate of uterine leiomyoma growth in the 3 trimesters of pregnancy.
methodsWe conducted a retrospective cohort study. Included were women who were diagnosed with uterine leiomyoma during pregnancy and had at least two sonographic measurements in different trimesters. Data regarding leiomyoma growth, recorded by ultrasound examination, during 1st 2nd and 3rd trimesters were collected from electronic patient records.
resultsTwo-hundred forty-eight uterine leiomyomas were included in the study. Leiomyoma area increased substantially in size between the 1st and 2nd trimesters (54.5% ± 75.9%, p = .007) and to a lesser degree between the 2nd and 3rd trimesters (17.9% ± 59.7%, NS). Evaluation of the change in size throughout the pregnancy - between 1st and 3rd trimesters revealed a significant increase of 95.9% ± 191.3% (p < .001). There was no significant growth of the leiomyomas between the 2nd and 3rd trimesters.
conclusionsUterine leiomyomas tend to grow substantially during the 1st trimester of pregnancy. This trend is attenuated later with minimal growth towards the end of gestation.
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