ArticleBMC infectious diseases2019
Intravenous-to-oral antibiotic switch therapy: a cross-sectional study in critical care units.
Article in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 64 citations in OpenAlex.
- Inpatients' willingness to accept antibiotic intravenous-to-oral switch therapy and its influencing factors: a qualitative study based on the Health Belief Model.BMC infectious diseases · 2026Article
- Choosing Wisely Canada climate-conscious recommendations for critical care medicine.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2026Article
- Cost analysis of a sequential antimicrobial therapy protocol in patients with pneumonia: A multicenter study.PloS one · 2026Observational
- Barriers to Compliance with National Guidelines Among Children Hospitalized with Community-Acquired Pneumonia in Vietnam and the Implications.Antibiotics (Basel, Switzerland) · 2025Article
- Estimated greenhouse gas emissions associated with unnecessary intravenous antimicrobials administered in the hospital setting.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Economic Impact in the Treatment of Coagulase-Negative Staphylococci Blood Cultures Contamination in a Middle-Income Country.Revista da Sociedade Brasileira de Medicina Tropical · 2025Article
- Market concentration of the Brazilian hospital medical supplementary health system.BMC health services research · 2024Article
- eHealth and mHealth in Antimicrobial Stewardship to Reduce Mortality in Empirical Antimicrobial Therapy and a Systematic Review with a Meta-Analysis of Adequate Therapy.Infectious disease reports · 2024Review
- Navigating fluoroquinolone resistance in Gram-negative bacteria: a comprehensive evaluation.JAC-antimicrobial resistance · 2024Review
- Review
- Assessment of frequency and types of drug interactions in intensive care units: a cross-sectional study.Annals of medicine and surgery (2012) · 2024Article
- Antimicrobial Use Among Hospitalized Neonates and Children; Findings and Implications from a Comprehensive Point Prevalence Survey Among General Tertiary Hospitals in Pakistan.Infection and drug resistance · 2024Article
- Oral Antibiotics for Bacteremia and Infective Endocarditis: Current Evidence and Future Perspectives.Microorganisms · 2023Review
- Antibiotic prescribing to inpatients in Limpopo, South Africa: a multicentre point-prevalence survey.Antimicrobial resistance and infection control · 2023Article
- Oral doxycycline to carbapenem-resistant Acinetobacter baumannii infection as a polymyxin-sparing strategy: results from a retrospective cohort.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023Article
- Opportunities, associations, and impact of early intravenous to oral antimicrobial switch for hospitalized patients in Ethiopia.SAGE open medicine · 2023Article
- Burden of enteral supplement interactions with common antimicrobial agents: a single-centre observational analysis.European journal of hospital pharmacy : science and practice · 2022Observational
- Antimicrobial Utilization among Neonates and Children: A Multicenter Point Prevalence Study from Leading Children's Hospitals in Punjab, Pakistan.Antibiotics (Basel, Switzerland) · 2022Article
- Brazilian private health system: history, scenarios, and trends.BMC health services research · 2022Article
- Predicting Oral Beta-lactam susceptibilities against Streptococcus pneumoniae.BMC infectious diseases · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to evaluate the oral switch (OS) stewardship intervention in the intensive care unit (ICU).
methodsThis was a retrospective study with a convenience sample in two Brazilian ICUs from different hospitals in patients with sepsis receiving antibiotic therapy. The stewardship intervention included OS in patients diagnosed with sepsis when clinical stability was achieved. The primary outcome was overall mortality. Other variables evaluated were as follows: cost of antimicrobial treatment, daily costs of intensive care, acute kidney injury, and length of stay.
resultsThere was no difference in mortality between the OS and non-OS groups (p = 0.06). Length of stay in the ICU (p = 0.029) was shorter and acute kidney injury incidence (p = 0.032) and costs of antimicrobial therapy (p < 0.001) were lower in the OS group.
conclusionOS stewardship programs in the ICU may be considered a safe strategy. Switch therapy reduced the cost and shortened the length of stay in ICUs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.